生物活性玻璃与玉米醇溶蛋白复合材料在骨组织工程中的应用

Q1 Materials Science

Biomedical Glasses Pub Date : 2018-07-01 DOI:10.1515/bglass-2018-0007

J. Hum, Shiva Naseri, A. Boccaccini

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引用次数: 8

摘要

摘要本研究的重点是开发基于玉米醇溶蛋白和生物活性玻璃的新型复合支架，用于骨组织工程。采用盐浸法制备了多孔聚合物基体。通过加入45S5生物活性玻璃颗粒，可以弥补生物活性的缺乏。然而，在盐浸过程中，生物活性玻璃的加入影响了玉米醇溶蛋白基质的塑化行为，这对压缩强度和降解行为产生了负面影响。本文描述了浸出过程，并解释了玉米醇溶蛋白在存在和不存在生物活性玻璃的情况下的不同行为

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Bioactive glass combined with zein as composite material for the application in bone tissue engineering

Abstract The present study has focused on the development of new composite scaffolds based on the combination of zein with bioactive glass for the application in bone tissue engineering. Porous polymeric matrices were produced by the salt leaching technique. By incorporating 45S5 bioactive glass particles the lack of bioactivity can be remedied. However, the addition of bioactive glass is influencing the plasticization behavior of the zein matrix during the salt leaching which negatively affects the compression strength as well as the degradation behavior. This paper describes the process during leaching and explains the different behavior of zein with and without the presence of bioactive glass

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来源期刊

Biomedical Glasses Materials Science-Surfaces, Coatings and Films

自引率

0.00%

发文量

审稿时长

17 weeks

期刊介绍： Biomedical Glasses is an international Open Access-only journal covering the field of glasses for biomedical applications. The scope of the journal covers the science and technology of glasses and glass-based materials intended for applications in medicine and dentistry. It includes: Chemistry, physics, structure, design and characterization of biomedical glasses Surface science and interactions of biomedical glasses with aqueous and biological media Modeling structure and reactivity of biomedical glasses and their interfaces Biocompatibility of biomedical glasses Processing of biomedical glasses to achieve specific forms and functionality Biomedical glass coatings and composites In vitro and in vivo evaluation of biomedical glasses Glasses and glass-ceramics in engineered regeneration of tissues and organs Glass-based devices for medical and dental applications Application of glasses and glass-ceramics in healthcare.