对乙酰氨基酚和氟氯西林治疗致5-氧脯氨酸酸中毒1例报告。

Q3 Medicine

Acute Medicine Pub Date : 2022-01-01 DOI:10.52964/AMJA.0892

P. van Montfort, F. Helmich, Gjm Mostard, D. van Twist

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引用次数: 1

摘要

高阴离子间隙代谢性酸中毒（HAGMA）是急诊科的常见诊断，需要进行系统的检查以确定和治疗根本原因。我们报告了一例罕见的HAGMA病例，这是由于长期使用对乙酰氨基酚（扑热息痛）和氟氯西林治疗引起的5-氧脯氨酸积累。本文描述了HAGMA的诊断检查，并强调了在潜在病因不清楚的情况下的方法和初步治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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5-Oxoproline acidosis caused by acetaminophen and flucloxacillin treatment - a case report.

High anion gap metabolic acidosis (HAGMA) is a common diagnosis in the emergency department, which requires a systematic work-up in order to identify and treat the underlying cause. We present an unusual case of HAGMA due to 5-oxoproline accumulation caused by prolonged treatment with both acetaminophen (paracetamol) and flucloxacillin. This paper describes the diagnostic work-up of HAGMA and emphasizes on the approach and initial treatment in case the underlying etiology is unclear.

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来源期刊

Acute Medicine Medicine-Emergency Medicine

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： These are usually commissioned by the editorial team in accordance with a cycle running over several years. Authors wishing to submit a review relevant to Acute Medicine are advised to contact the editor before writing this. Unsolicited review articles received for consideration may be included if the subject matter is considered of interest to the readership, provided the topic has not already been covered in a recent edition. Review articles are usually 3000-5000 words and may include tables, pictures and other figures as required for the text. Include 3 or 4 ‘key points’ summarising the main teaching messages.