Δ9-四氢大麻酚(THC)检测呈阳性的司机在采血过程中记录的症状的相关性

Q4 Medicine
W. Lechowicz, Joanna Gieroń
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引用次数: 0

摘要

多年来,大麻对道路安全的影响一直是许多争论的主题。近年来,由于在几个司法管辖区采取了旨在营销医用大麻的举措,这些辩论愈演愈烈。根据波兰法医毒理学家的说法,道路安全是一个关键问题,特别是在2012年11月在克拉科夫和2013年8月在波兰举行的关于确定适当浓度阈值的会议之后(Gierońet al.,2013)。这些阈值定义了“使用后”和“受影响”条件的限制,对波兰政府来说仍然不明确或不容易确定。明确评估给定浓度的血液Thc对精神运动表现的影响是非常困难的,而且在可预见的未来仍将如此。这项研究使用了107个随机选择的血液采集方案,每个四氢大麻酚浓度在1至10 ng/ml之间有10个方案,在此基础上分析了与受试者外表和行为相关的13个特征。这些特征包括:面部皮肤(苍白、正常或红色)、口齿不清、情绪和行为(愉快、健谈、吵闹或沉默)、心率、瞳孔(正常、扩张或收缩)、瞳孔对光的反应、罗贝格测试、指鼻测试、从地上捡起物体以及对时间和地点的意识。与受访者的外表和行为相关的13个特征中,有5个没有异常(步态、罗贝格测试、手指到鼻子测试、从地上捡起物体以及对时间和地点的意识)。研究发现,协议中观察和记录的症状不足以决定Thc对心理运动表现的影响。特征性症状(愉快和健谈)的出现频率不高于测试浓度的十分之三。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation of symptoms registered during blood collection from drivers who tested positive for Δ9-tetrahydrocannabinol (THC)
The impact of marijuana on road safety has been the subject of many debates over the years. These debates have intensified in recent years due to initiatives carried out in several jurisdictions aimed at marketing medical cannabis. According to Polish forensic toxicologists, road safety is a key issue, especially following the conferences in November 2012 in Kraków and in 2013 in Augustów (Gieroń et al., 2013), Poland, on the determination of appropriate concentration thresholds. These thresholds, defining the limit for the ‘after use’ and ‘under the influence’ conditions, are still not unambiguous or easy to determine for the Polish government. An unambiguous assessment of the impact of a given concentration of blood Thc on psychomotor performance is very difficult, and will remain so in the foreseeable future. This study used 107 randomly selected blood collection protocols, with 10 protocols for each THC concentration ranging from 1 to 10 ng/ml, on the basis of which thirteen features related to the external appearance and behaviour of the tested individuals were analysed. These features were: facial skin (pale, normal or red), slurred speech, mood and behaviour (cheerful, talkative, rowdy or reticent), heart rate, pupils (normal, dilated or contracted), reaction of pupils to light, the romberg test, the finger-to-nose test, picking up objects from the ground and awareness of time and place. Five of the thirteen features related to the appearance and behaviour of the respondents showed no abnormalities (gait, the romberg test, the finger-to-nose test, picking up objects from the ground, and awareness of time and place). The study found that the symptoms observed and recorded in the protocols are insufficient to make a decision about the impact of Thc on psychomotor performance. The characteristic symptoms (cheerfulness and talkativeness) occurred no more frequently than in 3 out of 10 of the concentrations tested.
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来源期刊
Z Zagadnien Nauk Sadowych
Z Zagadnien Nauk Sadowych Medicine-Pathology and Forensic Medicine
CiteScore
0.30
自引率
0.00%
发文量
15
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