直接心脏压迫装置增强心脏生物力学和功能。

IF 12.8 1区工程技术 Q1 ENGINEERING, BIOMEDICAL

Annual Review of Biomedical Engineering Pub Date : 2022-04-08 DOI:10.1146/annurev-bioeng-110220-025309

J. Bonnemain, P. D. del Nido, E. Roche

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引用次数: 4

摘要

随着医疗、心脏移植和机械循环支持（MCS）设备（如左心室辅助设备和全人工心脏）的进步，终末期心力衰竭的治疗已经发生了重大变化。然而，目前的多组分灭菌剂设备本质上与血液接触，可能导致潜在的并发症，包括泵血栓形成、出血、中风和溶血。为了解决这些问题并避免血液接触，提出了从心外膜表面压迫衰竭心脏的概念，并设计了直接心脏压迫（DCC）装置。我们回顾了与DCC相关的基本概念，介绍了研究和商业化阶段的基础设备和最新设备，并讨论了临床翻译和采用该技术所需的里程碑。《生物医学工程年度评论》第24卷预计最终在线出版日期为2022年6月。请参阅http://www.annualreviews.org/page/journal/pubdates用于修订估算。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Direct Cardiac Compression Devices to Augment Heart Biomechanics and Function.

The treatment of end-stage heart failure has evolved substantially with advances in medical treatment, cardiac transplantation, and mechanical circulatory support (MCS) devices such as left ventricular assist devices and total artificial hearts. However, current MCS devices are inherently blood contacting and can lead to potential complications including pump thrombosis, hemorrhage, stroke, and hemolysis. Attempts to address these issues and avoid blood contact led to the concept of compressing the failing heart from the epicardial surface and the design of direct cardiac compression (DCC) devices. We review the fundamental concepts related to DCC, present the foundational devices and recent devices in the research and commercialization stages, and discuss the milestones required for clinical translation and adoption of this technology. Expected final online publication date for the Annual Review of Biomedical Engineering, Volume 24 is June 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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来源期刊

Annual Review of Biomedical Engineering 工程技术-工程：生物医学

CiteScore

18.80

自引率

0.00%

发文量

期刊介绍： Since 1999, the Annual Review of Biomedical Engineering has been capturing major advancements in the expansive realm of biomedical engineering. Encompassing biomechanics, biomaterials, computational genomics and proteomics, tissue engineering, biomonitoring, healthcare engineering, drug delivery, bioelectrical engineering, biochemical engineering, and biomedical imaging, the journal remains a vital resource. The current volume has transitioned from gated to open access through Annual Reviews' Subscribe to Open program, with all articles published under a CC BY license.