N-烷基氨基甲酸酯合成不对称脲的改进

IF 2 Q2 CHEMISTRY, ORGANIC
SynOpen Pub Date : 2023-08-21 DOI:10.1055/a-2157-5925
Prachi Ramteke, Dinesh Kumar Tanwar, M. Gill
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引用次数: 0

摘要

报道了一种通过氨基甲酸酯制备N,N’-烷基芳基脲和N,N′-二烷基脲的高效、经济、简便、绿色的方法。这种改进的方法不含任何有害试剂,如光气、异氰酸酯等,并且显示出宽的底物范围和良好到优异的产率。与文献报道相比,该程序操作简单,具有潜在的可扩展性,对合成这些重要的基序非常有利。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

IMPROVED SYNTHESIS OF UNSYMMETRICAL UREAS VIA N-ALKYL CARBAMATES

IMPROVED SYNTHESIS OF UNSYMMETRICAL UREAS VIA N-ALKYL CARBAMATES
An efficient, cost-effective, easy and green method is reported for the preparation of N,N’-alkyl aryl ureas and N,N’-dialkylureas via carbamates. This improved procedure is devoid of any hazardous reagents such as phosgent, isocyanates etc. and has shown a broad substrate scope with good to excellent yields. As compared to literature reports, this procedure is operationally simple, potentially scalable and significantly benign to synthesize these important motifs.
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来源期刊
SynOpen
SynOpen CHEMISTRY, ORGANIC-
CiteScore
2.30
自引率
4.00%
发文量
35
审稿时长
6 weeks
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