McKeown和Ivor-Louis食管切除术治疗第三食管下段癌症的疗效比较

IF 0.6 Q4 ONCOLOGY
Indian Journal of Surgical Oncology Pub Date : 2025-04-01 Epub Date: 2023-05-25 DOI:10.1007/s13193-023-01770-4
Naveen Kumar, Amitabha Mandal, Sandeep Bhoriwal, S V S Deo, Sachidanand Jee Bharati, Sunil Kumar
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引用次数: 0

摘要

食管癌常用的手术方法是McKeown和Ivor Lewis食管癌切除术。Ivor Lewis食管切除术主要用于下段食管癌。在此,我们分析了两种治疗下食管癌的手术,以寻找围手术期和生存结果。从计算机数据库中检索手术数据,纳入2014 - 2019年接受下段食管癌手术的患者。分析两种手术的人口学细节、围手术期结果、并发症发生率、总生存率和无病生存率。共90例下段食管癌患者行食管切除术。McKeown组RLN麻痹及吻合口漏发生率较高。McKeown组和Ivor Lewis组的5年OS分别为49%和58.3%,而5年DFS分别为41%和63.9%。在Ivor Lewis组中,通过比较两种组织学亚型,估计SCC和腺癌的5年OS分别为74%和26.3% (p p = 0.07)。本研究未发现McKeown食管切除术与Ivor Lewis手术治疗下三分之一食管癌的围手术期和生存结果有显著差异。有必要进行一项前瞻性试验来观察这种差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of Outcomes After McKeown and Ivor Lewis Esophagectomy for Lower Third Esophageal Cancer.

The commonly performed surgical procedures for esophageal cancer are McKeown and Ivor Lewis esophagectomy. The Ivor Lewis esophagectomy is mainly performed for lower esophageal cancer. Herein, we analyzed both procedures performed for lower esophageal cancer to look for perioperative and survival outcomes. The surgical data was retrieved from the computerized database, and the patients operated on for lower esophageal cancer from 2014 to 2019 were included. Both procedures were analyzed for demographic details, perioperative outcomes, complication rate, and overall and disease-free survivals. A total of 90 patients undergoing esophagectomy for lower esophageal cancer. RLN palsy and anastomotic leak rate were higher in the McKeown group. The estimated 5-year OS was 49% and 58.3% in the McKeown and Ivor Lewis groups, respectively, whereas the estimated 5-year DFS was 41% and 63.9%. In the Ivor Lewis group, on comparing both histological subtypes, the estimated 5-year OS was 74% and 26.3% (p < 0.05) whereas the DFS was 74.5% and 42% (p = 0.07) for SCC and adenocarcinoma, respectively. This study did not find a significant difference in the perioperative as well as survival outcomes comparing McKeown esophagectomy with the Ivor Lewis procedure for lower third esophageal cancer. A prospective trial is warranted to see the difference.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
190
期刊介绍: The Indian Journal of Surgical Oncology aims to encourage and promote clinical and research activities pertaining to Surgical Oncology. It also aims to bring in the concept of multidisciplinary team approach in management of various cancers. The Journal would publish original article, point of technique, review article, case report, letter to editor, profiles of eminent teachers, surgeons and instititions - a short (up to 500 words) of the Cancer Institutions, departments, and oncologist, who founded new departments.
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