PD51-11 报告实施强化术后恢复（ERAS）方案后根治性膀胱切除术的结果

IF 5.9 2区医学 Q1 UROLOGY & NEPHROLOGY

Journal of Urology Pub Date : 2020-04-01 DOI:10.1097/JU.0000000000000953.011

S. Williams, M. Cumberbatch, A. Kamat, P. Kerr, J. McGrath, H. Djaladat, J. Collins, I. Jubber, V. Packiam, G. Steinberg, Eugene K Lee, W. Kassouf, P. Black, Y. Cerantola, J. Catto, S. Daneshmand

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引用次数: 1

摘要

UCB具有较高的pT3期频率（比值比[OR]，3.84；95%置信区间[CI]，1.63e9.03；p[0.002）和淋巴结转移风险（OR，2.58；95%CI，1.15e5.76；p[0.02）、输尿管边缘阳性（OR 12.18；95%CI，4.62e32.13；p<0.0001）和膀胱周围软组织边缘阳性（OR12.31；95%CI 5.15e29.41；p<0.00001）与C-UCB患者相比，根治性膀胱切除术后的状态。尽管PV-UCB和C-UCB之间的CSM没有差异（危险比[HR]，1.40；95%CI，0.82e2.40；p[0.22），但PV-UCB的生存结果（OM）比接近显著性边界的C-UCB差（HR，1.62；95%CI 0.98e2.68；p[0.06）当根据其他临床病理特征进行调整时。结论：在调整其他临床病理参数后，与CUCB相比，PV-UCB与不良临床病理特征和更差的OM密切相关，UCB的PV组织学是影响总生存率的独立预后因素。

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PD51-11 REPORTING RADICAL CYSTECTOMY OUTCOMES FOLLOWING IMPLEMENTATION OF ENHANCED RECOVERY AFTER SURGERY (ERAS) PROTOCOLS

UCB had a higher frequency of stage pT3 (odds ratio [OR], 3.84; 95% confidence interval [CI], 1.63e9.03; p[0.002) and risk of lymph node metastasis (OR, 2.58; 95% CI, 1.15e5.76; p[0.02), ureteral marginpositive (OR 12.18; 95% CI, 4.62e32.13; p<0.00001), and perivesical soft tissue margin-positive (OR 12.31; 95% CI, 5.15e29.41; p<0.00001) status after radical cystectomy than those with C-UCB. Although there was no difference in CSM (hazard ratio [HR], 1.40; 95% CI, 0.82e2.40; p[0.22) between PV-UCB and C-UCB, PV-UCB had worse survival outcomes (OM) than C-UCB approaching the borderline of significance (HR, 1.62; 95% CI, 0.98e2.68; p[0.06) when adjusted for other clinicopathological characteristics. CONCLUSIONS: PV-UCB was strongly associated with adverse clinicopathological features and worse OM compared to CUCB after adjusting other clinicopathological parameters, and PV histology of UCB is an independent prognostic factor for overall survival.

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来源期刊

Journal of Urology 医学-泌尿学与肾脏学

CiteScore

11.50

自引率

7.60%

发文量

3746

审稿时长

2-3 weeks

期刊介绍： The Official Journal of the American Urological Association (AUA), and the most widely read and highly cited journal in the field, The Journal of Urology® brings solid coverage of the clinically relevant content needed to stay at the forefront of the dynamic field of urology. This premier journal presents investigative studies on critical areas of research and practice, survey articles providing short condensations of the best and most important urology literature worldwide, and practice-oriented reports on significant clinical observations.