高通量实验是欧洲及其他地区学术有机化学家可获得的技术**

IF 6.1 Q1 CHEMISTRY, MULTIDISCIPLINARY
Dr. Xisco Caldentey, Dr. Eugénie Romero
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引用次数: 1

摘要

近年来,高通量实验(High-Throughput Experimentation, HTE)作为一种节省时间和成本的有力工具,已被应用于有机化学的反应优化和反应发现。如果这项技术最初是由工业界开发的,并作为一种常规方法使用,那么包括欧洲在内的一些学术研究人员仍在挑战HTE作为通用和日常使用技术的可及性。其中一个原因可能是此类设施开发的昂贵成本,这通常涉及机器人自动化、专门的研究团队和昂贵的分析仪器。本文旨在以最小的仪器和成本揭示批量HTE的可访问性,以帮助有机化学家加速新合成方法的发现和优化,从而降低他们的成本并增强他们的创新研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

High-Throughput Experimentation as an Accessible Technology for Academic Organic Chemists in Europe and Beyond**

High-Throughput Experimentation as an Accessible Technology for Academic Organic Chemists in Europe and Beyond**

For years now, High-Throughput Experimentation (HTE) have been applied to organic chemistry for reaction optimization and reaction discovery as a powerful tool for time and cost reduction. If this technology has been first developed by and for industry, and used as a routine method today, some academic researchers, including in Europe, are still challenging the accessibility of HTE as a general and daily used technology. One of the reasons is probably the expensive cost of such facilities development, which generally involves automation with robots, dedicated research teams, and expensive analytical instrumentation. This paper aims at bringing to light the accessibility of batch HTE with a minimum of instrumentation and cost, in order to help organic chemists to accelerate the discovery and optimization of new synthetic methodology, leading them to reduce their costs and empower their innovative research.

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CiteScore
7.30
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