水碱性条件下槲皮素-3-芦丁苷选择性氘化的温和绿色方案

IF 1.1 Q3 CHEMISTRY, MULTIDISCIPLINARY

Current Green Chemistry Pub Date : 2019-10-25 DOI:10.2174/2213346106666190916105514

Anxhela Akolli, S. Moretti, Francesca Mangiavacchi, Bonifacio Monti, C. Santi

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引用次数: 2

摘要

本文报道了一种使用生物相容性碱和D2O作为氘源和溶剂进行芦丁选择性氘化的简便、经济的方法。该方案是良性和廉价的，在非常温和的条件下提供良好的结果，允许减少氧化氘的需水量。h - nmr可以方便地跟踪C-H/C-D交换的位置和氘化水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mild and Green Protocol for Selective Deuteration of Quercetin-3-ORutinoside (Rutin) Under Aqueous Basic Conditions

A convenient and cost-effective method for selective deuteration of rutin using biologically compatible bases and D2O both as a deuterium source and a solvent is herein reported. The protocol is benign and inexpensive affording good results in very mild conditions allowing to reduce the required amount of deuterium oxide. The position of the C-H/C-D exchange and the level of deuteration can be conveniently followed by 1H-NMR.

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来源期刊

Current Green Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

4.30

自引率

13.60%

发文量