一项荟萃分析:单次针灸治疗可降低痛风性关节炎患者尿酸水平并减轻疼痛

IF 0.2 4区医学 Q4 INTEGRATIVE & COMPLEMENTARY MEDICINE

Acupuncture & Electro-Therapeutics Research Pub Date : 2021-04-01 DOI:10.3727/036012921X16164310686815

Pei Liu, Li Deng, Yiwen Lv, Huachong Xu, Huan Zhao, Xiao-yin Chen

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引用次数: 0

摘要

目的:通过比较西药与单针治疗痛风性关节炎的疗效，系统评价单针治疗痛风性关节炎的有效性和安全性。方法:两名审稿人收集并筛选文献，提取相关信息，包括:病程、随机方法、干预措施、疗程、检测指标、不良反应等。目的:通过比较西药与单针治疗痛风性关节炎的疗效，系统评价单针治疗痛风性关节炎的有效性和安全性。方法:两名审稿人收集并筛选文献，提取相关信息，包括:病程、随机方法、干预措施、疗程、检测指标、不良反应等。进行质量评价、meta分析、发表偏倚和敏感性分析。主要指标包括总有效率、血清尿酸，次要指标包括疼痛积分、不良事件、随访脱落等。结果:筛选出26项rct，共2048名受试者。结果显示，单针治疗痛风性关节炎总有效率高于西药组[OR = 4.33, 95% CI(3.22, 5.82)]，且在降低尿酸水平方面具有一定的临床优势[MD = -68.39, 95% CI(-97)]。[47， -39.31]，镇痛效果与西药相当。单针治疗组无不良反应发生。结论:单针治疗痛风性关节炎比西医治疗更有效、更安全。然而，由于纳入的文献质量较低，这些结果应谨慎解释;需要更多科学的临床随机对照试验来验证单针治疗痛风性关节炎的效果。

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Single Acupuncture Treatment Can Reduce the Level of Uric Acid and Alleviating Pain in Gouty Arthritis, a Meta-Analysis

Objective: The effectiveness and safety of single acupuncture on gouty arthritis were systematically evaluated by comparing the effectiveness of Western medicine and single acupuncture on gouty arthritis. Methods: Two reviewers collected and screened the literature, and extracted relevant information, including: course of disease, random method, intervention measures, course of treatment, detection indicators, adverse reactions, etc. Objective: The effectiveness and safety of single acupuncture on gouty arthritis were systematically evaluated by comparing the effectiveness of Western medicine and single acupuncture on gouty arthritis. Methods: Two reviewers collected and screened the literature, and extracted relevant information, including: course of disease, random method, intervention measures, course of treatment, detection indicators, adverse reactions, etc. Quality assessment, meta-analysis, publication bias and sensitivity analysis were performed. The main outcomes included total effective rate and serum uric acid, while secondary outcomes included pain integral, adverse events and follow-up shedding etc. Results: 26 RCTs were screened out, with a total of 2048 participants. The results show that the total effective rate of single acupuncture treatment of gouty arthritis is higher than that of the Western medicine group [OR = 4.33, 95% CI (3.22, 5.82)], and it had a certain clinical advantage in reducing the level of uric acid [MD = –68.39, 95% CI(–97. 47, –39.31)], the analgesic effect is equivalent to that of Western medicine. There were no adverse reactions were reported in the single acupuncture treatment group. Conclusion: The results show that single acupuncture is more effective and safer than Western medicine in the treatment of gouty arthritis. However, due to the low quality of the included literature, these results should be interpreted with caution; more scientific clinical RCTs are needed to verify the effect of single acupuncture on gouty arthritis.

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来源期刊

Acupuncture & Electro-Therapeutics Research 医学-全科医学与补充医学

CiteScore

0.50

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of the journal is to provide an international forum for the exchange of ideas and promotion of basic and clinical research in acupuncture, electro-therapeutics, and related fields. The journal was established in order to make acupuncture and electro-therapeutics a universally acceptable branch of medicine through multidisciplinary research based on scientific disciplines. The final goal is to provide a better understanding of both the beneficial and adverse effects of these treatments in order to supplement or improve existing methods of diagnosis, prognosis, treatment, and prevention of diseases in both Western and Oriental medicine.