软骨下成形术治疗膝关节疼痛伴骨髓损伤的疗效观察

Nathan M. Krebs, James L. Kehoe, Michael J. Van Wagner, C. Ríos-Bedoya
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引用次数: 6

摘要

膝骨性关节炎患者MRI上的症状性骨髓病变与关节进行性恶化和需要关节置换手术的进展风险增加密切相关。本研究评估膝关节镜辅助软骨下成形术(即软骨稳定)在改善自评视觉模拟量表(VAS)疼痛评分、关节成形术转换率和患者满意度方面的疗效。方法对12例膝关节疼痛伴慢性软骨下骨髓病变行膝关节镜辅助软骨下成形术的患者进行回顾性资料回顾和电话调查。12例患者的随访时间平均为36个月(12至51个月),分析患者自我报告的术前和术后配对VAS评分,以及关节置换术转换率和患者满意度。结果结果显示,术前平均VAS评分与术后6周VAS评分相比,从7.58降至1.83 (p < 0.001),术前平均VAS评分与术后最终VAS评分相比,从7.58降至1.60 (p < 0.001)。接受关节镜下软骨下成形术后患者的人口统计学和临床资料(如年龄、身高、体重、BMI、症状持续时间)以及全关节置换术翻修率无统计学意义(p > 0.05)。在12例患者中,2例(16.7%)患者转为全膝关节置换术。结论:在本研究中,膝关节镜下辅助软骨下成形术治疗伴有症状性骨髓病变的骨关节炎与VAS疼痛评分的临床显著改善相关。此外,在36个月的随访中,接受软骨下成形术的患者转换为全膝关节成形术的比例很低(16.7%)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Efficacy of Subchondroplasty for the Treatment of Knee Pain Associated with Bone Marrow Lesions
CONTEXT Symptomatic bone marrow lesions on MRI in patients with knee osteoarthritis are strongly associated with progressive deterioration of the joint and an increased risk of progression requiring joint replacement surgery. This study evaluates the efficacy of knee arthroscopy with adjunctive subchondroplasty (i.e. cartilage stabilization) to improve self-rated visual analog scale (VAS) pain scores, rate of conversion to arthroplasty, and patient satisfaction levels. METHODS A retrospective chart review and phone survey was performed on 12 patients who had undergone knee arthroscopy with adjunctive subchondroplasty for knee pain associated with chronic subchondral bone marrow lesions on MRI. Follow-up for the 12 patients was 36 months on average (range of 12 to 51 months), self-reported paired preoperative and postoperative VAS scores were analyzed in addition to rate of conversion to arthroplasty and patient satisfaction. RESULTS The results demonstrated statistically significant reductions in mean preoperative VAS scores versus six-week postoperative VAS scores from 7.58 to 1.83 (p < 0.001) in addition to significant reductions in mean preoperative VAS scores to final postoperative VAS scores from 7.58 to 1.60 (p < 0.001). There was no statistically significant association (p > 0.05) with patients’ demographic and clinical data (e.g., age, height, weight, BMI, length of symptoms) and rate of revision to total arthroplasty after receiving the arthroscopic subchondroplasty procedure. Out of the 12 patients, two (16.7%) patients went on to conversion to total knee arthroplasty. CONCLUSIONS In this series, knee arthroscopy with adjunctive subchondroplasty for the treatment of osteoarthritis with symptomatic bone marrow lesions was associated with clinically significant improvements in VAS pain scores. Furthermore, patients who underwent subchondroplasty had a low rate (16.7%) of conversion to total knee arthroplasty at 36-month follow-up.
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