{"title":"海绵亚拟虾炭黑曲霉的化学成分研究","authors":"Muhammad Syahrur Ramadhan, Riga Riga, E. Hakim","doi":"10.55251/jmbfs.9467","DOIUrl":null,"url":null,"abstract":"An endophytic fungus identified as Aspergillus carbonarius was obtained from from sea sponge Aaptos suberitioides. Phytochemical study of fungal A. carbonarius led to the isolation of four compounds (1-4) of which compound 1 was a new isocoumarin derivative, (R)-6-hydroxy-3-(1-hydroxypropan-2-yl)-8-methoxyisocoumarin. The others (compounds 2-4) were the known compounds. Isolation of these compounds was performed using vacuum liquid dan column chromatography. The structure elucidation and identification of these compounds were conducted with the help of NMR and HR-ESI-MS spectroscopic data. All isolated compounds (1-4) were tested for their antibacterial activity against five bacterial strains and displayed inactive activity against all tested microorganisms.","PeriodicalId":16348,"journal":{"name":"Journal of microbiology, biotechnology and food sciences","volume":" ","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CHEMICAL CONSTITUENTS OF Aspergillus carbonarius ISOLATED FROM MARINE SPONGE Aaptos suberitoides\",\"authors\":\"Muhammad Syahrur Ramadhan, Riga Riga, E. Hakim\",\"doi\":\"10.55251/jmbfs.9467\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"An endophytic fungus identified as Aspergillus carbonarius was obtained from from sea sponge Aaptos suberitioides. Phytochemical study of fungal A. carbonarius led to the isolation of four compounds (1-4) of which compound 1 was a new isocoumarin derivative, (R)-6-hydroxy-3-(1-hydroxypropan-2-yl)-8-methoxyisocoumarin. The others (compounds 2-4) were the known compounds. Isolation of these compounds was performed using vacuum liquid dan column chromatography. The structure elucidation and identification of these compounds were conducted with the help of NMR and HR-ESI-MS spectroscopic data. All isolated compounds (1-4) were tested for their antibacterial activity against five bacterial strains and displayed inactive activity against all tested microorganisms.\",\"PeriodicalId\":16348,\"journal\":{\"name\":\"Journal of microbiology, biotechnology and food sciences\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2023-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of microbiology, biotechnology and food sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55251/jmbfs.9467\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"FOOD SCIENCE & TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of microbiology, biotechnology and food sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55251/jmbfs.9467","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
CHEMICAL CONSTITUENTS OF Aspergillus carbonarius ISOLATED FROM MARINE SPONGE Aaptos suberitoides
An endophytic fungus identified as Aspergillus carbonarius was obtained from from sea sponge Aaptos suberitioides. Phytochemical study of fungal A. carbonarius led to the isolation of four compounds (1-4) of which compound 1 was a new isocoumarin derivative, (R)-6-hydroxy-3-(1-hydroxypropan-2-yl)-8-methoxyisocoumarin. The others (compounds 2-4) were the known compounds. Isolation of these compounds was performed using vacuum liquid dan column chromatography. The structure elucidation and identification of these compounds were conducted with the help of NMR and HR-ESI-MS spectroscopic data. All isolated compounds (1-4) were tested for their antibacterial activity against five bacterial strains and displayed inactive activity against all tested microorganisms.
期刊介绍:
The Journal of Microbiology, Biotechnology and Food Sciences is an Open Access, peer-reviewed online scientific journal published by the Faculty of Biotechnology and Food Sciences (Slovak University of Agriculture in Nitra). The major focus of the journal is regular publishing of original scientific articles, short communications and reviews about animal, plant and environmental microbiology (including bacteria, fungi, yeasts, algae, protozoa and viruses), microbial, animal and plant biotechnology and physiology, microbial, plant and animal genetics, molecular biology, agriculture and food chemistry and biochemistry, food control, evaluation and processing in food science and environmental sciences.