FADOI对意大利医院内科慢性肾脏疾病和贫血的调查

IF 0.3 Q3 MEDICINE, GENERAL & INTERNAL
P. Bocchi, A. Montagnani, Michele Meschi, F. Pomero, P. Piccolo, A. Valerio, G. Gussoni, D. Manfellotto, F. Dentali, Chronic Kidney Disease and Anaemia In Internal Medicine (CKD-AIM) FADOI Study Group
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引用次数: 0

摘要

慢性肾脏病(CKD)患者贫血与生活质量下降以及发病率、死亡率和住院率增加有关。这反过来又影响了医疗成本和医疗资源的利用。CKD贫血的发病机制多种多样且复杂。它们包括内源性红细胞生成素(EPO)的产生减少、绝对和/或功能性缺铁(由于炎症导致铁调素水平升高)、尿毒症毒素导致骨髓对EPO的反应减弱、红细胞(RBC)寿命缩短以及维生素B12或叶酸缺乏。[…]
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FADOI survey on chronic kidney disease and anaemia in internal medicine departments of Italian hospitals
The presence of anaemia in patients with chronic kidney disease (CKD) is associated with decreased quality of life, along with increased morbidity, mortality, and hospitalization rates. This, in turn, affects healthcare costs and the utilization of medical resources. The mechanisms involved in anaemia of CKD are diverse and complex. They include reduced production of endogenous erythropoietin (EPO), absolute and/or functional iron deficiency (due to inflammation leading to elevated levels of hepcidin), the diminished response of the bone marrow to EPO due to uraemic toxins, the shortened lifespan of red blood cells (RBC), and deficiencies in vitamin B12 or folic acid. [...]
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来源期刊
Italian Journal of Medicine
Italian Journal of Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
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0.00%
发文量
3
审稿时长
10 weeks
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