蓖麻籽油在治疗银屑病中药乳液配方中的药效学应用及评价

Q4 Pharmacology, Toxicology and Pharmaceutics

International Journal of Drug Delivery Technology Pub Date : 2023-03-25 DOI:10.25258/ijddt.13.1.45

Sujit Pathare, Snehal S. Babar, Manoj Tare, Dwarkadas Baheti, H. Tare, Nitin Deshmukh, Vijay Sable

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引用次数: 0

摘要

炎症和免疫介导的皮肤病，银屑病。银屑病在全世界的人身上都很常见。药物通过局部途径最有效地治疗皮肤病。试图通过使用含有蓖麻籽油的乳化凝胶组合物来提高银屑病的局部治疗效果。为了产生凝胶，将提取物与液体石蜡油、橄榄油和椰子油以及Carbopol 936和940胶凝剂混合。乳液的粘度和光泽度是使用草药提取物实现的。当测试物理化学标准时，发现开发的配方在各个方面都是可接受的。这些发现意味着局部凝胶治疗银屑病正变得更加有效。由于乳化凝胶提高了渗透性，草药凝胶具有更高的效果。

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Pharmacobotanical Application of Ricinus communis Seed Oil in Formulation and Evaluation of Herbal Emulgel for the Treatment of Psoriasis

Infl ammatory and immune-mediated skin disease, psoriasis. It’s common for psoriasis to be seen in people all over the globe. Drugs are most eff ectively delivered through the topical route for treating skin conditions. An attempt was made to increase the eff ectiveness of topical treatment for psoriasis by using emulgel compositions containing Ricinus communis seed oil. In order to create the gel, the extract was mixed with liquid paraffi n, olive and coconut oils, and Carbopol 936 and 940 gelling agents. The viscosity and glossiness of the emulgel were achieved using herbal extracts. When tested for physicochemical criteria, the developed formulations were found to be acceptable in every way. These fi ndings imply that topical gel therapy for psoriasis is becoming more eff ective. Due to the emulgel improved penetration, the herbal gel has more eff ectiveness.

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来源期刊

International Journal of Drug Delivery Technology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： International Journal of Drug Delivery Technology (IJDDT) provides the forum for reporting innovations, production methods, technologies, initiatives and the application of scientific knowledge to the aspects of pharmaceutics, including controlled drug release systems, drug targeting etc. in the form of expert forums, reviews, full research papers, and short communications.