水凝胶伤口敷料的研究进展与挑战

IF 4.7 3区 工程技术 Q2 ENGINEERING, BIOMEDICAL
Wenda Wang , Sarute Ummartyotin , Ravin Narain
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引用次数: 9

摘要

水凝胶由于其亲水性、可调节的化学、机械和生物特性,在伤口敷料中有着广阔的应用前景。然而,传统的水凝胶只能被动地参与创面的愈合过程,维持创面周围的水分,限制了创面的愈合效果。近年来,水凝胶伤口敷料的发展主要集中在机械活性黏附水凝胶和自适应水凝胶上,它们能够积极地加速伤口愈合过程。在本文中,我们首先回顾了两种水凝胶敷料的设计策略和作用机制,然后讨论了这两种水凝胶敷料在不同类型伤口治疗中的应用。最后,我们提出了用于伤口愈合的下一代“智能”水凝胶材料的未来发展趋势和研究机会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Advances and challenges on hydrogels for wound dressing

Hydrogels, due to their hydrophilic nature, tunable chemical, mechanical and biological properties, have shown great promises for wound dressing application. Nevertheless, conventional hydrogels can only passively participate in the wound healing process by maintaining the moisture around wound, which limits the wound healing efficacy. Recent developments of hydrogel wound dressings have focused on the mechanically active adhesive hydrogels and self-adapting hydrogels, which are able to actively accelerate the wound healing process. In this review, we first review the design strategies and function mechanisms of both types of hydrogel dressings, followed by the discussion on the application of those hydrogel dressings for the treatment of different type of wounds. Finally, we present the future trends and research opportunities for the development of next generation “smart” hydrogel materials for wound healing application.

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来源期刊
Current Opinion in Biomedical Engineering
Current Opinion in Biomedical Engineering Medicine-Medicine (miscellaneous)
CiteScore
8.60
自引率
2.60%
发文量
59
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