石墨烯的抗菌性能及其对PMMA压缩性能的增强作用

Q3 Biochemistry, Genetics and Molecular Biology

Biointerface Research in Applied Chemistry Pub Date : 2022-11-01 DOI:10.33263/briac134.393

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引用次数: 1

摘要

石墨烯及其衍生物因其优异的性能而备受关注。本研究旨在评估石墨烯的抗菌性能及其对聚甲基丙烯酸甲酯（PMMA）潜在骨替代物力学性能的增强作用。石墨烯的形态最初是通过场发射扫描电子显微镜（FESEM）观察到的。然后制备五种浓度的石墨烯（1、0.5、0.25、0.125和0.0625mg/mL），并评估其对金黄色葡萄球菌的抗菌性能。选择表现出最高抗菌性能的两种浓度，并将其与PMMA结合。石墨烯在0.5和1.0mg/mL浓度下表现出优异的抗菌性能。与未填充的PMMA相比，0.5mg/mL石墨烯增强的PMMA表现出高达48%的压缩强度增量和72%的压缩模量。总之，具有改进的生物和机械性能的PMMA复合材料有可能用作骨替代物。

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Antibacterial Properties of Graphene and its Reinforcement Effect on Compressive Properties of PMMA

Graphene and its derivatives have received significant attention due to their outstanding properties. This study aims to evaluate the antibacterial properties of graphene and its reinforcement effect on the mechanical properties of polymethyl methacrylate (PMMA) for potential bone substitution. The morphology of graphene was initially observed via a field emission scanning electron microscope (FESEM). Five concentrations of graphene (1, 0.5, 0.25, 0.125, and 0.0625 mg/mL) were then prepared, and its antibacterial properties were assessed against Staphylococcus aureus. Two concentrations that exhibited the highest antibacterial properties were selected and incorporated with PMMA. Graphene exhibited superior antibacterial properties at 0.5 and 1.0 mg/mL concentrations. The 0.5 mg/mL graphene-reinforced PMMA presented an increment of compressive strength by up to 48% and a compressive modulus of 72% compared to unfilled PMMA. In conclusion, the PMMA composite with improved biological and mechanical performance could be potentially used as a bone substitution.

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来源期刊

Biointerface Research in Applied Chemistry CHEMISTRY, APPLIED-

CiteScore

4.80

自引率

0.00%

发文量

256

期刊介绍： Biointerface Research in Applied Chemistry is an international and interdisciplinary research journal that focuses on all aspects of nanoscience, bioscience and applied chemistry. Submissions are solicited in all topical areas, ranging from basic aspects of the science materials to practical applications of such materials. With 6 issues per year, the first one published on the 15th of February of 2011, Biointerface Research in Applied Chemistry is an open-access journal, making all research results freely available online. The aim is to publish original papers, short communications as well as review papers highlighting interdisciplinary research, the potential applications of the molecules and materials in the bio-field. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible.