Seong Hyun Moon, Rahul Soangra, C. Frames, T. Lockhart
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引用次数: 1
摘要
帕金森病(PD)是一种影响黑质的神经退行性疾病,超过一半的PD患者被认为是跌倒的高危人群。最近,惯性测量单元(IMU)传感器在日常生活活动(ADL)的分类中显示出巨大的前景,例如行走,站立,坐着和躺着,被认为是日常生活中的正常运动。通过对PD患者进行纵向ADL监测,测量他们的身体活动水平,可以深入了解他们的跌倒机制。本研究招募了6例PD患者(平均年龄=74.3±6.5岁)和6例年轻健康受试者(平均年龄=19.7±2.7岁)。所有受试者被要求在L5-S1脊柱区域佩戴单个加速度计DynaPort MM+(运动监视器+,McRoberts BV, the Hague, Netherlands),采样频率为100 Hz,持续3天。受试者对他们所做的活动进行记录,只有在洗澡或进行其他水上活动时才取下传感器。由此产生的加速度使用高通和低通巴特沃斯滤波器进行滤波,以确定动态和静止活动。结果发现,健康青年受试者的动态活动(13.2%)明显多于PD受试者(7%),而PD受试者(92.9%)的静态活动明显多于年轻健康受试者(86.8%)。
THREE DAYS MONITORING OF ACTIVITIES OF DAILY LIVING AMONG YOUNG HEALTHY ADULTS AND PARKINSON’S DISEASE PATIENTS
Parkinson’s Disease (PD) is a neurodegenerative disorder affecting the substantia nigra, which leads to more than half of PD patients are considered to be at high risk of falling. Recently, Inertial Measurement Unit (IMU) sensors have shown great promise in the classification of activities of daily living (ADL) such as walking, standing, sitting, and laying down, considered to be normal movement in daily life. Measuring physical activity level from longitudinal ADL monitoring among PD patients could provide insights into their fall mechanisms. In this study, six PD patients (mean age=74.3±6.5 years) and six young healthy subjects (mean age=19.7±2.7 years) were recruited. All the subjects were asked to wear the single accelerometer, DynaPort MM+ (Motion Monitor+, McRoberts BV, The Hague, Netherlands), with a sampling frequency of 100 Hz located at the L5-S1 spinal area for 3 days. Subjects maintained a log of activities they performed and only removed the sensor while showering or performing other aquatic activities. The resultant acceleration was filtered using high and low pass Butterworth filters to determine dynamic and stationary activities. As a result, it was found that healthy young subjects performed significantly more dynamic activities (13.2%) when compared to PD subjects (7%), in contrast, PD subjects (92.9%) had significantly more stationary activities than young healthy subjects (86.8%).