Justina Ugwaha, N. Savage, W. Messina, Y. Wanga, E. Whelton, A. O’Donovan, M. J. O'Sullivan, B. O. Donnell, E. Moore
{"title":"生物阻抗传感器在离体乳腺癌检测中的应用","authors":"Justina Ugwaha, N. Savage, W. Messina, Y. Wanga, E. Whelton, A. O’Donovan, M. J. O'Sullivan, B. O. Donnell, E. Moore","doi":"10.29245/2578-2967/2021/1.1193","DOIUrl":null,"url":null,"abstract":"Bioimpedance is the opposition to flow of an applied electrical current through biological tissues1. Our research group designed and fabricated bipolar micro-sensors on the tip of a silicone probe, capable of measuring biological tissue impedance. It is known that the bioimpedance of cultured cancer cells differs substantially from that of healthy cell lines. We hypothesised that the bioimpedance of cancer in surgically excised human tissue would be significantly different to surrounding healthy tissue. To test this hypothesis, we designed a study to evaluate the bioimpedance of healthy and diseased breast tissue in surgically excised breast specimens. This manuscript reports the outcome of this study.","PeriodicalId":92397,"journal":{"name":"Journal of cancer treatment & diagnosis","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Ex-Vivo Detection of Breast Cancer with a Bio-Impedance Sensor\",\"authors\":\"Justina Ugwaha, N. Savage, W. Messina, Y. Wanga, E. Whelton, A. O’Donovan, M. J. O'Sullivan, B. O. Donnell, E. Moore\",\"doi\":\"10.29245/2578-2967/2021/1.1193\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bioimpedance is the opposition to flow of an applied electrical current through biological tissues1. Our research group designed and fabricated bipolar micro-sensors on the tip of a silicone probe, capable of measuring biological tissue impedance. It is known that the bioimpedance of cultured cancer cells differs substantially from that of healthy cell lines. We hypothesised that the bioimpedance of cancer in surgically excised human tissue would be significantly different to surrounding healthy tissue. To test this hypothesis, we designed a study to evaluate the bioimpedance of healthy and diseased breast tissue in surgically excised breast specimens. This manuscript reports the outcome of this study.\",\"PeriodicalId\":92397,\"journal\":{\"name\":\"Journal of cancer treatment & diagnosis\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-03-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of cancer treatment & diagnosis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29245/2578-2967/2021/1.1193\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cancer treatment & diagnosis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29245/2578-2967/2021/1.1193","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ex-Vivo Detection of Breast Cancer with a Bio-Impedance Sensor
Bioimpedance is the opposition to flow of an applied electrical current through biological tissues1. Our research group designed and fabricated bipolar micro-sensors on the tip of a silicone probe, capable of measuring biological tissue impedance. It is known that the bioimpedance of cultured cancer cells differs substantially from that of healthy cell lines. We hypothesised that the bioimpedance of cancer in surgically excised human tissue would be significantly different to surrounding healthy tissue. To test this hypothesis, we designed a study to evaluate the bioimpedance of healthy and diseased breast tissue in surgically excised breast specimens. This manuscript reports the outcome of this study.
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