对禽杆菌病肉鸡的血液形态学和生化指标进行了测定,并对25%多氧多辛和Tilmox进行了测定

A. Tyshkivska, V. Dukhnitsky, M. Tyshkivsky
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引用次数: 0

摘要

本文介绍了对KOBB-500肉鸡、未经治疗的鸟类细胞菌病患者和使用药物“多西环素”和“Tilmox25%”治疗的病禽的血液形态和生化参数的研究结果。研究表明,肉鸡禽细菌素病的特点是红细胞减少、低血红蛋白血症和红细胞压积降低。在按照治疗方案使用波多辛和替莫的实验组鸟类中,25%的红细胞计数、216小时血液中血红蛋白含量和红细胞压积均高于对照组:红细胞计数分别为-19%和36%;血红蛋白含量——在两个实验组的家禽中都增加了17%;红细胞压积-分别降低19%和23%(p≤0.05)。对照组肉鸡的鸟类细胞菌病患者血清蛋白质中发现异常蛋白血症,其中在实验的216h,总蛋白质和白蛋白分别降低了12%和34%。同时球蛋白的含量增加了32%。第2和第3个实验组的家禽血清中总蛋白和白蛋白含量在216小时时分别比对照指数增加了24%和33%(p≤0.05),白蛋白含量在两个实验组中都增加了56%。试验组肉鸡血清中球蛋白含量在试验的24~216小时内分别为10.72~11.98克/升和11.32~15.21克/升,而在用波多辛和替莫司25%处理的实验组家禽血清中,其活性在96h、120h和216h时的下降可能低于对照组。肉鸡鸟粪菌病对照组观察到低钙血症,而在处理的家禽2和3个实验组的血清中,24至216小时的总钙含量可能高于对照组。在对照组和2只实验鸟(波多辛)中观察到低磷酸盐血症,其血清中无机磷含量在216小时内分别比实验组3只(使用25%的替莫)低43%和23%。关键词:多西环素,替米考星,家禽呼吸道疾病,鼻杆菌,抗生素,生物利用度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Morphological and biochemical parameters of the blood of broiler chickens with ornithobacteriosis, and for the use of Poledoxin and Tilmox 25%
The article presents the results of studies of morphological and biochemical parameters of blood of broiler chickens KOBB-500, patients with ornithobacteriosis, who were not treated, and sick birds, for the treatment of which were used drugs "Poledoxin" (active substance - doxycycline hyclate) and "Tilmox 25%" (active substance - tilmicosin phosphate). Studies have shown that ornithobacteriosis in broiler chickens is characterized by erythrocytopenia, hypohemoglobinemia and decreased hematocrit. In the birds of the experimental groups, which in accordance with the treatment regimen used poledoxin and tilmox 25% erythrocyte count, hemoglobin content in the blood and hematocrit at 216 h of the experiment were higher than in the control: erythrocyte count - 19 and 36%, respectively; hemoglobin content - by 17% in poultry of both experimental groups; hematocrit - by 19 and 23%, respectively (p≤0.05). In the serum proteins of patients with ornithobacteriosis of broiler chickens of the control group was found dysproteinemia, in which at 216 h of the experiment there was a decrease in total protein and albumin by 12 and 34%, respectively. At the same time there was an increase in the content of globulins by 32%. The content of total protein and albumin in the serum of poultry 2 and 3 experimental groups increased and by 216 h exceeded the control index by 24 and 33% (p≤0.05), respectively, albumin - by 56% in poultry of both experimental groups. The content of globulins in the serum of poultry of the experimental groups for the period from 24 to 216 h of the experiment was in the range of 10.72 - 11.98 g / l, while in the control - 11.32 - 15.21 g / l. In the serum of broiler chickens of the control group for the period from 24 to 216 h increased the activity of alanine aminotransferase by 14%, while in the serum of poultry of experimental groups treated with poledoxin and tilmox 25% its activity decreased by 96, 120 and 216 h was probably less than in the control. Hypocalcemia was observed in the control group of broiler chickens ornithobacteriosis, whereas in the serum of poultry 2 and 3 experimental groups treated, the total calcium content in the period from 24 to 216 h was probably higher than in the control. Hypophosphatemia was observed in the control and 2 experimental birds (poledoxine), and the inorganic phosphorus content in their serum was 216 h lower than in the experimental group 3 birds (tilmox 25% was used) by 43 and 23%, respectively. Key words: doxycycline, tilmicosin, respiratory diseases of poultry, O. Rhinotracheale, antibiotics, bioavailability.
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