掺钬二氧化钛(Ho-TiO2)纳米催化剂的环境和治疗应用研究:光催化降解红皂素O染料的动力学和热力学研究

IF 2.5 4区材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nano Futures Pub Date : 2021-12-17 DOI:10.1088/2399-1984/ac446c

F. A. Jan, Wajidullah, R. Ullah, Salman, N. Ullah, A. Salam

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引用次数: 2

摘要

通过溶胶-凝胶法合成了二氧化钛（TiO2）和掺钬二氧化钛（Ho-TiO2）纳米颗粒（NP）。通过紫外-可见（UV–Vis）光谱、x射线衍射（XRD）、能量色散x射线分析、扫描电子显微镜（SEM）、傅立叶变换红外光谱和光致发光（PL）光谱对合成的纳米颗粒进行了表征。还对合成的NP进行了DNA结合、抗菌、溶血和抗氧化分析，以寻找其治疗应用。成功地用Ho掺杂TiO2将带隙从3.10降低到2.88eV。SEM和XRD分析表明，掺杂使TiO2和Ho-TiO2纳米颗粒都表现出四方结构，颗粒的形貌得到改善，团聚减少。TiO2的PL发射强度也随着掺杂而降低。两种催化剂对番红O染料的降解均遵循一级动力学。对于裸TiO2和Ho-TiO2 NP，给定染料光降解的计算活化能分别为51.7和35.2 KJ mol−1。180分钟后，使用纯TiO2和Ho-TiO2分别观察到84%和87%的染料降解。在两种催化剂的低浓度（20ppm）和最佳剂量（0.035g）下发现染料的高降解率。发现藏红O染料的降解速率随着培养基的温度和pH的增加而增加。一项DNA结合研究表明，Ho-TiO2 NP更能与人类DNA结合。一项抗菌活性研究表明，与纯TiO2相比，Ho-TiO2 NP对革兰氏阴性和革兰氏阳性菌株都更有效。溶血试验表明TiO2和Ho-TiO2纳米粒子是非生物相容性的。与裸露的TiO2相比，Ho-TiO2 NP显示出更高的抗氧化活性。

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An investigation into the environmental and therapeutic applications of holmium-doped titanium dioxide (Ho-TiO2) nanocatalysts: a kinetic and thermodynamic study of the photocatalytic degradation of Safranin O dye

Titanium dioxide (TiO2) and holmium-doped titanium dioxide (Ho-TiO2) nanoparticles(NPs) were synthesized through a sol gel route. The synthesized NPs were characterized by ultraviolet-visible (UV–Vis) spectroscopy, x-ray diffraction (XRD), energy dispersive x-ray analysis, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy, and photoluminescence (PL) spectroscopy. DNA binding, antibacterial, hemolysis, and antioxidant assays of the synthesized NPs were also carried out in order to find their therapeutic applications. Successful doping of TiO2 with Ho reduced the bandgap from 3.10 to 2.88 eV. SEM and XRD analysis showed that both TiO2 and Ho-TiO2 NPs exhibit a tetragonal structure and the morphology of the particles improved and agglomeration reduced as a result of doping. The PL emission intensity of TiO2 also reduced with doping. The degradation of Safranin O dye over both the catalysts followed first-order kinetics. The calculated activation energy for the photodegradation of the given dye was found to be 51.7 and 35.2 KJ mol−1 for bare TiO2 and Ho-TiO2 NPs, respectively. After 180 min, 84% and 87% dye degradation was observed using pure TiO2 and Ho-TiO2, respectively. A high percent of degradation of the dye was found at a low concentration (20 ppm) and at optimal dosage (0.035 g) of both the catalysts. The rate of Safranin O dye degradation was found to increase with an increase in temperature and pH of the medium. A DNA binding study revealed that Ho-TiO2 NPs are more capable of binding to human DNA. An antibacterial activity study showed that Ho-TiO2 NPs were more efficient against both gram-negative and gram-positive bacterial strains compared to pure TiO2. Hemolysis assay showed that TiO2 and Ho-TiO2 NPs are non-biocompatible. Ho-TiO2 NPs showed higher anti-oxidant activity compared to bare TiO2.

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来源期刊

Nano Futures Chemistry-General Chemistry

CiteScore

4.30

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0.00%

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期刊介绍： Nano Futures mission is to reflect the diverse and multidisciplinary field of nanoscience and nanotechnology that now brings together researchers from across physics, chemistry, biomedicine, materials science, engineering and industry.