200例埃及银屑病患者的临床病理和实验室特征

IF 0.2 Q4 DERMATOLOGY
S. Aboeldahab, M. El-Hamd, Rehab Hamed Bakla, Essam El-Din Abdel-Aziz Nada
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引用次数: 0

摘要

背景银屑病是一种常见而复杂的多因素疾病,遗传和外源因素都有助于激活免疫反应。目的本研究旨在评估上埃及Sohag埃及银屑病患者的临床、人口统计学和实验室特征。患者和方法本研究是一项基于医院的横断面研究,对200名埃及银屑病患者进行了研究。所有患者都接受了完整的人口统计学、临床和实验室评估。结果埃及银屑病患者200例,平均年龄42.83±17.3岁;60%为男性,53%来自农村,47%为吸烟者,66%有阳性家族史,91%为渐进性发作,75%为渐进性病程,平均病程为6.99±3.9个月。银屑病的主要相关症状是瘙痒,占72%。寻常型银屑病最常见,占69.5%。78%的银屑病患者上肢是最常见的发病部位。在51.5%的银屑病患者中,季节变化是最常见的加重因素。31%的银屑病患者出现了缺铁性贫血。29.5%的银屑病患者合并肝脏疾病,4.5%的银屑病患者出现丙型肝炎病毒感染。代谢综合征和应激分别在36%和21%的银屑病患者中检测到。结论医护人员和患者应注意银屑病合并症的早期发现,避免出现重大并发症。对压力的认识及其具体治疗应被视为银屑病患者治疗的一个组成部分。对埃及银屑病患者进行肝炎筛查很重要。有银屑病家族史的患者应避免近亲结婚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinicodemographic and laboratory features of 200 Egyptian psoriatic patients
Background Psoriasis is a common and complex multifactorial disease, in which both genetic and extrinsic factors contribute to activating an immunological reaction. Objectives This study aimed to evaluate the clinical, demographic, and laboratory characteristics of Egyptian psoriatic patients in Sohag, Upper Egypt. Patients and methods This study was a cross-sectional hospital-based study conducted on 200 Egyptian psoriatic patients. All the patients were subjected to complete demographic, clinical, and laboratory evaluations. Results Of the 200 Egyptian patients with psoriasis, the mean age was 42.83±17.3 years; 60% were males, 53% were from rural areas, 47% were smokers, 66% were with positive family history, 91% were with gradual onset, 75% were with a progressive course, and 6.99±3.9 months was the mean duration of the diseases. The main associated symptom with psoriasis was itching in 72%. Psoriasis vulgaris was the most common type in 69.5%. Upper limbs were the most commonly affected sites in 78% of the psoriatic patients. Seasonal variation was the most common exacerbating factor in 51.5% of psoriatic patients. Iron-deficiency anemia was detected in 31% of the psoriatic patients. Liver diseases were associated comorbidities with 29.5% of psoriatic patients and hepatitis C virus infection was presented in 4.5% of psoriatic patients. Metabolic syndrome and stress were detected in 36 and 21% of psoriatic patients, respectively. Conclusion The healthcare providers and patients should be aware of the early detection of associated comorbidities with psoriasis to avoid major complications. The recognition of stress and its specific treatment should be considered an integral part of the treatment of psoriatic patients. Screening for hepatitis is important in Egyptian psoriatic patients. Consanguineous marriage should be avoided in patients with a family history of psoriasis.
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