Clinical features and chest CT findings in moderate and severe COVID-19 patients: an analysis of 506 cases from Wuhan Huoshenshan Hospital

Objective: To investigate the clinical features and chest CT findings in moderate and severe COVID-19 patients Methods: A total of 506 patients with COVID-19 treated in Wuhan Huoshenshan Hospital during February 9 to March 9, 2020 were enrolled in the study, including 365 moderate cases and 141 severe cases The clinical features and chest CT findings were retrospectively analyzed Chi-square test and Fisher's exact probability were used for data analysis Results: The proportions of patients with diabetes and hypertension in severe group were significantly higher than those in moderate group (χ2=9 377 and 15 085, P 10 cm and involved all five lung lobes (P<0 01) The severe patients had more imaging signs of air bronchogram, bronchovascular thickening, pleural thickening, mediastinal or hilar lymphnodes enlargement, pleural effusion and pericardial effusion than moderate patients (χ2=33 357, 11 114, 14 580, 5 978, 45 731 and 6 623, P<0 05 or <0 01) Conclusion: There are differences in clinical features and chest CT findings between moderate and severe patients, and chest CT findings can be used as important criteria for clinical classification Copyright © 2020 by the Chinese Medical Association