反刍动物肠道微生物群:失调的重要性、发展和替代疗法

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Nahlah Albakri, R. Amasha, M. M. Aly
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引用次数: 0

摘要

微生物群是在哺乳动物肠道中定植的一群微生物。在生命的最初几年里,肠道微生物组经历了改变,并且在成年期非常多样化,这取决于各种情况。肠道微生物,尤其是反刍动物肠道菌群,正受到越来越多的关注。无论是在基础研究还是应用领域,随着高通量测序技术的进步和成本的降低,肠道微生物,特别是反刍动物微生物越来越受到人们的关注。反刍动物的微生物群与其宿主一起发生变化,并受到微生物间相互作用、环境暴露和宿主特性的影响。然而,任何生物体的核心功能微生物群都要常规得多。不幸的是,微生物培养物的脆弱生长比在疾病环境下容易受到入侵,这可能会影响各种微生物物种的丰度,导致生态失调。因此,本综述的目的是提供反刍动物肠道微生物相关性的广泛总结,以及研究影响微生物群的变量和替代治疗方法,如益生菌,益生元,粪便移植和瘤胃变形,所有这些都已被证明对解决生态失调有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ruminant gut microbiota: importance, development, and alternative therapeutics for dysbiosis
The microbiome is a population of microbes that colonized in mammalian gut. During the first few years of life, the gut microbiome undergoes alteration and is very diverse in adulthood, depends upon various of circumstances. Gut microbes, particularly gut flora in ruminants, are receiving more and more attention. Intestinal microbes, particularly ruminant microorganisms, have attracted an increasing amount of attention as high-throughput sequencing technology has improved and costs have decreased, whether in the fundamental research or application fields. The ruminant microbiome changes in conjunction with its host and it is influenced by inter-microbial interactions, environmental exposures, and host properties. However, any organism's core functional microbiome is much more conventional. Unfortunately, the fragile growth ratio of the microbial culture is susceptible to incursions under illness circumstances, which may affect the abundance of various microbial species, resulting to dysbiosis. As a result, the purpose of this review is to provide a broad summary of the relevance of ruminant gut microorganisms, as well as to investigate variables that influence the microbiota and alternative therapeutics such as probiotics, prebiotics, fecal transplantation, and rumen transfiguration, all of which have been shown to be effective in addressing dysbiosis.
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来源期刊
Journal of Contemporary Medical Sciences
Journal of Contemporary Medical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
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发文量
65
审稿时长
12 weeks
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