tmg -壳三霉素的化学合成

IF 1.2 4区化学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Carbohydrate Chemistry Pub Date : 2021-01-01 DOI:10.1080/07328303.2021.2009504

Yunqin Zhang , Guozhi Xiao

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引用次数: 0

摘要

TMG-chitotriomycin是一种新发现的β- n -乙酰氨基葡萄糖苷酶(GlcNAcase)抑制剂，对昆虫和真菌GlcNAcase具有特异性。化学合成是解决TMG-chitotriomycin可得性问题的可靠有效手段，有利于深入研究其生物活性。到目前为止，已经报道了四种不同的合成tmg -壳三霉素的途径。本文对化学合成tmg -壳三霉素的研究进展进行了综述。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Chemical synthesis of TMG-chitotriomycin

TMG-chitotriomycin is a recently discovered β-N-acetylglucosaminidase (GlcNAcase) inhibitor, specific for insect and fungal GlcNAcases. Chemical synthesis is a reliable and effective means to solve the attainability issues of TMG-chitotriomycin, which could facilitate in-depth studies of its biological activities. Thus far, four different synthetic routes toward TMG-chitotriomycin have been reported. Herein, we provide a comprehensive review on the chemical synthesis of TMG-chitotriomycin.

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来源期刊

Journal of Carbohydrate Chemistry 化学-生化与分子生物学

CiteScore

2.10

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： The Journal of Carbohydrate Chemistry serves as an international forum for research advances involving the chemistry and biology of carbohydrates. The following aspects are considered to fall within the scope of this journal: -novel synthetic methods involving carbohydrates, oligosaccharides, and glycoconjugates- the use of chemical methods to address aspects of glycobiology- spectroscopic and crystallographic structure studies of carbohydrates- computational and molecular modeling studies- physicochemical studies involving carbohydrates and the chemistry and biochemistry of carbohydrate polymers.