金黄色葡萄球菌耐药性模式变化与新冠肺炎暴发

IF 0.2 Q4 SURGERY

Formosan Journal of Surgery Pub Date : 2023-02-02 DOI:10.1097/FS9.0000000000000023

P. Sookaromdee, V. Wiwanitkit

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引用次数: 0

摘要

*新冠肺炎自2020年1月以来一直存在于研究环境中。人类的麻雀。尽管医学的进步降低了它们的流行率，但它们仍然是一个主要问题。由于手术部位感染，住院费用显著增加。金黄色葡萄球菌是导致手术部位感染的主要病原体之一。抗抗生素城市中心的金黄色葡萄球菌病原体在手部感染中的识别率最高，但对耐甲氧西林菌株不断变化的药物敏感性状况知之甚少。然而，耐药病原体会严重影响临床问题。例如，金黄色葡萄球菌定植增加了心脏手术患者手术部位感染的发生率。在世界各地的临床环境中，常规耐药性监测已经进行了很长时间。来自中印国家的关于金黄色葡萄球菌中万古霉素耐药性分布的数据是作者希望在本文中介绍和讨论的。简言之，这种类型的严重抗生素耐药性与反复感染、万古霉素治疗无效和不良临床结果有关。作为一种能够抵抗我们所有治疗尝试的适应性病毒，病原体将继续给外科医生带来挑战。有人认为，万古霉素治疗严重金黄色葡萄球菌感染的疗效正在下降，这是由于万古霉素治疗疗效的下降，同时万古霉素在易感范围内的最低抑制浓度增加（所谓的最低抑制剂量蠕变）。金黄色葡萄球菌对万古霉素耐药性的模式变化与新冠肺炎疫情的关系是本文作者的主要关注点。表1显示了基于本地公共数据的环境中的模式信息(http://narst.dmsc.moph.go.th/data/AMR%2020000-2021-12M.pdf）。与一年相比

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Pattern change of vancomycin resistance in Staphylococcus aureus and COVID-19 outbreak: A note

*COVID-19 has been existed in the study setting since January 2020. Spart of humanity. Despite the fact that medical advancements have decreased their prevalence, they continue to be a major issue. Hospitalization costs are significantly raised as a result of surgical site infections. Staphylococcus aureus is one of the major pathogens that causes of surgical site infection. Antibiotic-resistant urban centers have seen the highest prevalence of S. aureus pathogen identification in hand infections, but little is known about the methicillin-resistant strains’ changing drug sensitivity profiles. However, the resistant pathogen can seriously impact clinical issues. For instance, S. aureus colonization increases the incidence of surgical site infection in heart surgery patients. In clinical settings all throughout the world, routine medication resistance monitoring has been carried out for a long time. The data from an Indochina nation regarding the distribution of vancomycin resistance in S. aureus is what the authors would like to present and discuss in this article. In short, this type of severe antibiotic resistance is linked to recurrent infections, the ineffectiveness of vancomycin treatment, and subpar clinical results. As an adaptive virus that can resist all of our therapeutic attempts, the pathogen will continue to present surgeons with challenges. It has been suggested that vancomycin is losing its effectiveness in treating severe S. aureus infections due to the decline in vancomycin treatment efficacy that is accompanied by increases in vancomycin minimum inhibitory concentration within the susceptible range (so-called minimum inhibitory concentration creep). The pattern change of vancomycin resistance in S. aureus in relation to the COVID-19 outbreak is the authors’ primary focus in this article. Table 1 displays the information about the pattern in our environment based on local public data (http://narst.dmsc.moph.go.th/ data/AMR%202000-2021-12M.pdf). When compared with a year

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来源期刊

Formosan Journal of Surgery SURGERY-

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

11 weeks

期刊介绍： Formosan Journal of Surgery, a publication of Taiwan Surgical Association, is a peer-reviewed online journal with Bimonthly print on demand compilation of issues published. The journal’s full text is available online at http://www.e-fjs.org. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository.