P.26不同饮食干预的肝脏转谷氨酰胺酶2水平比较

IF 0.9 4区医学 Q4 PERIPHERAL VASCULAR DISEASE

Artery Research Pub Date : 2020-12-01 DOI:10.2991/artres.k.201209.039

Elif Oztemiz, S. Dogan, B. Tuna

{"title":"P.26不同饮食干预的肝脏转谷氨酰胺酶2水平比较","authors":"Elif Oztemiz, S. Dogan, B. Tuna","doi":"10.2991/artres.k.201209.039","DOIUrl":null,"url":null,"abstract":"Purpose/Background/Objectives: Tissue transglutaminase (TG2) is a highly expressed protein especially in endothelial cells. TG2 has several functions including transamidation activity which is important in several processes such as extracellular matrix remodeling [1]. TG2 activity takes place in aortic stiffness regulation and atherosclerotic plaque formation [2]. One of the most effective implementation for atheroprone state and general cardiovascular health is calorie restriction (CR). In addition, lipid accumulation and subsequent metabolic disorders can be regulated by CR and longer lifespan can be achieved [3]. In this study we aimed to determine the effect of different CR application types on liver TG2 levels of female mice fed up to 82 weeks old age.","PeriodicalId":8466,"journal":{"name":"Artery Research","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"P.26 Liver Transglutaminase 2 Level Comparison Among Different Dietary Interventions\",\"authors\":\"Elif Oztemiz, S. Dogan, B. Tuna\",\"doi\":\"10.2991/artres.k.201209.039\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose/Background/Objectives: Tissue transglutaminase (TG2) is a highly expressed protein especially in endothelial cells. TG2 has several functions including transamidation activity which is important in several processes such as extracellular matrix remodeling [1]. TG2 activity takes place in aortic stiffness regulation and atherosclerotic plaque formation [2]. One of the most effective implementation for atheroprone state and general cardiovascular health is calorie restriction (CR). In addition, lipid accumulation and subsequent metabolic disorders can be regulated by CR and longer lifespan can be achieved [3]. In this study we aimed to determine the effect of different CR application types on liver TG2 levels of female mice fed up to 82 weeks old age.\",\"PeriodicalId\":8466,\"journal\":{\"name\":\"Artery Research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2020-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Artery Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2991/artres.k.201209.039\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Artery Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2991/artres.k.201209.039","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}

引用次数: 0

摘要

目的/背景/目的：组织谷氨酰胺转胺酶（TG2）是一种高表达蛋白，尤其是在内皮细胞中。TG2具有多种功能，包括转酰胺活性，这在细胞外基质重塑等几个过程中很重要[1]。TG2活性发生在主动脉硬化调节和动脉粥样硬化斑块形成中[2]。对动脉粥样硬化状态和一般心血管健康最有效的实施之一是热量限制（CR）。此外，CR可以调节脂质积累和随后的代谢紊乱，并可以延长寿命[3]。在本研究中，我们旨在确定不同CR应用类型对82周龄雌性小鼠肝脏TG2水平的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

P.26 Liver Transglutaminase 2 Level Comparison Among Different Dietary Interventions

Purpose/Background/Objectives: Tissue transglutaminase (TG2) is a highly expressed protein especially in endothelial cells. TG2 has several functions including transamidation activity which is important in several processes such as extracellular matrix remodeling [1]. TG2 activity takes place in aortic stiffness regulation and atherosclerotic plaque formation [2]. One of the most effective implementation for atheroprone state and general cardiovascular health is calorie restriction (CR). In addition, lipid accumulation and subsequent metabolic disorders can be regulated by CR and longer lifespan can be achieved [3]. In this study we aimed to determine the effect of different CR application types on liver TG2 levels of female mice fed up to 82 weeks old age.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Artery Research Medicine-Cardiology and Cardiovascular Medicine

CiteScore

1.70

自引率

16.70%

发文量

审稿时长

13 weeks

期刊介绍： Artery Research is the official journal of the Association for Research into Arterial Structure and Physiology (ARTERY) which promotes the advancement of knowledge and dissemination of information concerning the pathophysiology, epidemiology, detection, investigation and treatment of arterial structure and function. The journal publishes original research articles, review articles, perspectives, case-studies, letters to the Editor, short communications and images. All submitted material is subject to a strict peer-review process.