抗菌光动力疗法在喉切除术后语音康复中的应用

Q3 Medicine

Biomedical Photonics Pub Date : 2021-04-18 DOI:10.24931/2413-9432-2021-10-1-11-16

S. Shinkarev, S. V. Boldyrev, A. P. Zagadaev, V. Podolsky, V. Borisov, Y. I. Kostyushina

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引用次数: 3

摘要

本文探讨喉切除术后患者的语音康复问题。现代修复喉部发声功能的可能性，以及延长假体使用寿命的方法。本文介绍了用氯型光敏剂Radagel进行抗菌光动力治疗(PDT)预防假体感染的方法。与对照组(6.8个月)相比，对声带假体进行抗菌PDT的平均手术时间增加到11.9个月，对照组每月使用150mg氟康唑进行预防。作者开发的方法可以显著延长义肢的使用寿命，无不良事件，患者耐受良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Antimicrobial photodynamic therapy in voice rehabilitation of patients after laryngectomy

The article is devoted to the problem of voice rehabilitation of patients after laryngectomy. Modern possibilities of repairing laryngeal vocal function, methods for extending the lifetime of voice prostheses are considered. The author’s method of prevention of infection of vocal prostheses using the antimicrobial photodynamic therapy (PDT) with chlorin-type photosensitizer Radagel is presented. Performing antimicrobial PDT of vocal prostheses increased the average operating time to 11.9 months compared to the control group (6.8 months), where a monthly dose of 150 mg of fluconazole was used for prevention. The method developed by the authors makes it possible to significantly extend the lifetime of vocal prostheses, is devoid of adverse events, is well tolerated by patients.

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来源期刊

Biomedical Photonics Medicine-Surgery

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The main goal of the journal – to promote the development of Russian biomedical photonics and implementation of its advances into medical practice. The primary objectives: - Presentation of up-to-date results of scientific and in research and scientific and practical (clinical and experimental) activity in the field of biomedical photonics. - Development of united Russian media for integration of knowledge and experience of scientists and practitioners in this field. - Distribution of best practices in laser medicine to regions. - Keeping the clinicians informed about new methods and devices for laser medicine - Approval of investigations of Ph.D candidates and applicants.