William Irving, Cameron Whittaker, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Jeff Smith
{"title":"侏儒兔大疱性角膜病","authors":"William Irving, Cameron Whittaker, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Jeff Smith","doi":"10.1053/j.jepm.2023.07.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Bullous keratopathy (BK) is an excessive accumulation of fluid in the cornea resulting in severe edema and protrusion. Based on the literature search, naturally occurring BK has not been reported in a rabbit.</p></div><div><h3>Case description</h3><p>A two-year-old female neutered dwarf rabbit (<span><em>Oryctolagus cuniculus</em><em> domesticus</em></span><span>) presented for worsening corneal edema of the left eye. The left eye was diagnosed with BK that was fluorescein<span> negative. Optical coherence tomography<span><span><span><span> revealed profound corneal lamellar separation typical of BK. The patient was anaesthetized and a temporary tarsorrhaphy (TT) was placed using 5/0 silk with fluid line stents in the upper and lower eyelids. The patient was treated with </span>ofloxacin ophthalmic solution, atropine ophthalmic solution, and oral </span>meloxicam. Following 10 days of TT the corneal thickness improved but edema progressed to occupy most of the cornea. An area of corneal infiltrate could then be seen. A fungal infection was suspected and topical </span>voriconazole 1% was added to the treatment regimen. Following two months of topical therapy the patient healed with mild fibrosis associated with the infiltrated area.</span></span></span></p></div><div><h3>Conclusions and case relevance</h3><p>Rabbits can be affected by naturally occurring bullous keratopathy and in this case healing was achieved following a temporary tarsorrhaphy and extended medical therapy.</p></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"47 ","pages":"Pages 23-26"},"PeriodicalIF":0.5000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bullous keratopathy in a dwarf rabbit (Oryctolagus cuniculus domesticus)\",\"authors\":\"William Irving, Cameron Whittaker, Kelly Caruso, Benjamin Reynolds, Paul McCarthy, Jeff Smith\",\"doi\":\"10.1053/j.jepm.2023.07.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Bullous keratopathy (BK) is an excessive accumulation of fluid in the cornea resulting in severe edema and protrusion. Based on the literature search, naturally occurring BK has not been reported in a rabbit.</p></div><div><h3>Case description</h3><p>A two-year-old female neutered dwarf rabbit (<span><em>Oryctolagus cuniculus</em><em> domesticus</em></span><span>) presented for worsening corneal edema of the left eye. The left eye was diagnosed with BK that was fluorescein<span> negative. Optical coherence tomography<span><span><span><span> revealed profound corneal lamellar separation typical of BK. The patient was anaesthetized and a temporary tarsorrhaphy (TT) was placed using 5/0 silk with fluid line stents in the upper and lower eyelids. The patient was treated with </span>ofloxacin ophthalmic solution, atropine ophthalmic solution, and oral </span>meloxicam. Following 10 days of TT the corneal thickness improved but edema progressed to occupy most of the cornea. An area of corneal infiltrate could then be seen. A fungal infection was suspected and topical </span>voriconazole 1% was added to the treatment regimen. Following two months of topical therapy the patient healed with mild fibrosis associated with the infiltrated area.</span></span></span></p></div><div><h3>Conclusions and case relevance</h3><p>Rabbits can be affected by naturally occurring bullous keratopathy and in this case healing was achieved following a temporary tarsorrhaphy and extended medical therapy.</p></div>\",\"PeriodicalId\":15801,\"journal\":{\"name\":\"Journal of Exotic Pet Medicine\",\"volume\":\"47 \",\"pages\":\"Pages 23-26\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Exotic Pet Medicine\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1557506323000599\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Exotic Pet Medicine","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1557506323000599","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Bullous keratopathy in a dwarf rabbit (Oryctolagus cuniculus domesticus)
Background
Bullous keratopathy (BK) is an excessive accumulation of fluid in the cornea resulting in severe edema and protrusion. Based on the literature search, naturally occurring BK has not been reported in a rabbit.
Case description
A two-year-old female neutered dwarf rabbit (Oryctolagus cuniculus domesticus) presented for worsening corneal edema of the left eye. The left eye was diagnosed with BK that was fluorescein negative. Optical coherence tomography revealed profound corneal lamellar separation typical of BK. The patient was anaesthetized and a temporary tarsorrhaphy (TT) was placed using 5/0 silk with fluid line stents in the upper and lower eyelids. The patient was treated with ofloxacin ophthalmic solution, atropine ophthalmic solution, and oral meloxicam. Following 10 days of TT the corneal thickness improved but edema progressed to occupy most of the cornea. An area of corneal infiltrate could then be seen. A fungal infection was suspected and topical voriconazole 1% was added to the treatment regimen. Following two months of topical therapy the patient healed with mild fibrosis associated with the infiltrated area.
Conclusions and case relevance
Rabbits can be affected by naturally occurring bullous keratopathy and in this case healing was achieved following a temporary tarsorrhaphy and extended medical therapy.
期刊介绍:
The Journal of Exotic Pet Medicine provides clinicians with a convenient, comprehensive, "must have" resource to enhance and elevate their expertise with exotic pet medicine. Each issue contains wide ranging peer-reviewed articles that cover many of the current and novel topics important to clinicians caring for exotic pets. Diagnostic challenges, consensus articles and selected review articles are also included to help keep veterinarians up to date on issues affecting their practice. In addition, the Journal of Exotic Pet Medicine serves as the official publication of both the Association of Exotic Mammal Veterinarians (AEMV) and the European Association of Avian Veterinarians (EAAV). The Journal of Exotic Pet Medicine is the most complete resource for practitioners who treat exotic pets.