褪黑素作为帕金森病睡眠障碍的一线治疗？

IF 1.3 Q4 NEUROSCIENCES

Progress in Neurology and Psychiatry Pub Date : 2021-10-01 DOI:10.1002/pnp.728

C. Cox, A. Mackett

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引用次数: 0

摘要

据报道，高达88%-98%的帕金森病患者存在睡眠障碍；甚至在运动症状出现之前，就可能出现各种睡眠障碍。快速眼动睡眠行为障碍（RBD）可导致暴力做梦行为，在帕金森病中的患病率为20%至50%，但目前尚不清楚该疾病的最佳治疗方法。在这里，作者考虑褪黑激素是否是治疗RBD的有效药物选择。

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Melatonin as first‐line treatment for sleep disorders in Parkinson's disease?

Sleep disturbance has been reported in up to 88%–98% of Parkinson's disease patients; various sleep disorders can present even before motor symptoms. Rapid eye movement sleep behaviour disorder (RBD), which can lead to violent dream enactment behaviour, has a prevalence in Parkinson's disease of 20% to 50% but best management of the condition is unclear. Here, the authors consider whether melatonin is an effective pharmacological option to manage RBD.

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来源期刊

Progress in Neurology and Psychiatry NEUROSCIENCES-

CiteScore

1.70

自引率

8.30%

发文量

期刊介绍： Progress in Neurology and Psychiatry is published nine times a year, and is a journal for specialists in secondary care, GPs with an interest in neurology and psychiatry, community psychiatric nurses and other specialist healthcare professionals. Articles cover management, news updates and opinion in all areas of neurology and psychiatry.