子痫后可逆性脑病综合征的临床与影像学分析

Fakhrurrazy Fakhrurrazy, Herly Maulida Surdhawati
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引用次数: 0

摘要

后部可逆性脑病综合征(PRES)是一种罕见的临床神经放射学疾病,在文献中并不常见,这是一种最近发现的综合征,临床特征为头痛、意识模糊、癫痫发作和视力丧失,影像学表现为双侧皮质和皮质下水肿,主要是大脑后部病变(主要是枕顶叶)。后部可逆性脑病综合征是严重子痫前期/子痫的一种罕见并发症。本研究的目的是通过临床和放射学方法报告先兆子痫的PRES病例。我们报告一例女性,34岁,主诉为强直阵挛性全身性癫痫发作和突发性头痛。该患者妊娠8个月,最近通过剖宫产终止妊娠。患者出现意识丧失、视力障碍、右肢体无力等症状,在治疗过程中症状逐渐好转。实验室检查结果为HELLP综合征(溶血、肝酶升高和血小板减少)。头部CT扫描显示左顶枕区低密度病变,T2W和T2FLAIR ADC MAPS MRI显示右、左顶枕高密度病变。可以得出结论,已有报道的子痫伴PRES的病例,其症状包括头痛、癫痫发作、精神状态障碍、视觉障碍。子痫患者的PRES和HELLP综合征之间的病理关系描述不多。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CLINICAL AND RADIOLOGICAL APPROACH OF POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME ON ECLAMPSIA
Posterior reversible encephalopathy syndrome (PRES) is rare clinico-neuroradiologic condition and not  commonly reported in the literature, a recently recognized syndrome characterized clinically by  headache, confusion, seizure and visual loss associated, with imaging findings of bilateral cortical and  subcortical oedema, predominantly posterior cerebral lesions (mainly occipito-parietal). Posterior  reversible encephalopathy syndrome is an uncommon complication of severe preeclampsia/ eclampsia.  The objective of this study is to report PRES case on eclampsia with clinical and radiological approach. We  report a case of woman, 34 years old woman, with chief complaint tonic clonic general seizure and  sudden headache previously. This patient had pregnancy 8 gestational month and had pregnancy  termination with cesarean section recently. Patient had loss of consciousness, vision disturbance, and  weakness of right extremities, all this symptom become well during treatment. The result of laboratory  examination was HELLP syndrome (haemolysis, elevated liver enzymes and low-platelets). Head CT scan  showed hypodense lesion in left parietooccipital region and MRI on T2W and T2FLAIR ADC MAPS found  hyperintens lesion in right and left parietooccipital. Then it can be concluded that it have been reported  cases of eclampsia with PRES with symptom of headache, seizure, mental status disturbance, visual  disturbances. The pathological association between PRES and HELLP syndrome in a patient with eclampsia  is poorly described.
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