{"title":"Werner综合征或成人早衰症:一种罕见的模仿硬皮病的疾病","authors":"Jasleen Sandhu, Ankita Tuknayat","doi":"10.4103/ejdv.ejdv_12_22","DOIUrl":null,"url":null,"abstract":"Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.","PeriodicalId":40542,"journal":{"name":"Egyptian Journal of Dermatology and Venereology","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Werner syndrome or adult progeria: a rare scleroderma mimicker\",\"authors\":\"Jasleen Sandhu, Ankita Tuknayat\",\"doi\":\"10.4103/ejdv.ejdv_12_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.\",\"PeriodicalId\":40542,\"journal\":{\"name\":\"Egyptian Journal of Dermatology and Venereology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Egyptian Journal of Dermatology and Venereology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/ejdv.ejdv_12_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Egyptian Journal of Dermatology and Venereology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ejdv.ejdv_12_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Werner syndrome or adult progeria: a rare scleroderma mimicker
Werner syndrome, a premature aging disorder, is a rare cause of pseudoscleroderma and can present with a multitude of clinical features involving the skin, endocrine and cardiovascular systems. Although genetic, the disease has its onset in puberty and cutaneous features like graying of hair, atrophic sclerotic skin, recurrent ulcers, and dyspigmentation are the first to manifest. All these features usually mislead the clinician to make a diagnosis of systemic sclerosis. A similar case is being presented and the importance of differentiating these two disorders is being discussed.