基于纳米技术的药物输送系统治疗癌症宫颈癌:综述

IF 1.4 4区 材料科学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
N. Mishra, M. Singhai, Ghanshyam Das Gupta, B. Khurana, Daisy Arora, Sumel Ashique
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引用次数: 0

摘要

癌症是一个全球性的公共卫生问题;在美国,它是第二大死亡原因。此外,癌症由癌症细胞的不同亚型和可变成分组成,可能导致连续的致癌作用。它可以根据开始于身体的部位进行分类,如乳腺癌症或癌症。癌症侵袭宫颈细胞,最常见的是在过渡区,当宫颈内腺细胞转化为宫颈外鳞状细胞时。根据肿瘤的程度和大小,癌症有多种治疗方法,通常需要手术、放疗和化疗。重要的是要有一个有效的药物输送系统,可以提高治疗效果,以克服传统疗法的限制,并获得更高的癌症治疗效果,从而成功治疗癌症。此外,这些疗法比传统疗法更安全。尽管已经创建了许多纳米载体,但只有少数几个获得了临床批准,可以将抗癌药物输送到可以看到其预测活性的靶区。除了发布的专利外,本综述还介绍了各种说明纳米载体价值的研究报告。最近发表了一些关于纳米载体结构的出版物、临床证据和专利记录,加强了对肿瘤管理的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanotechnology-Based Drug Delivery Systems for the Treatment of Cervical Cancer: A Comprehensive Review
Cancer is a global public health issue; in the United States, it is the second leading cause of death. Furthermore, cancer, which consists of distinct subtypes of cancer cells and variable components, may cause a continuum of carcinogenesis. It can be categorized according to the part where it begins in the body, such as breast cancer or cervix cancer. Cervical cancer attacks cervix cells, most commonly in the transition area, when the endocervix's glandular cells transform into the exocervix's squamous cells. Cervical cancer is treated in several methods depending on the degree and size of the tumour and frequently entails surgery, radiotherapy, and chemotherapy. It is vital to have an effective drug delivery system that may increase the treatment effectiveness to overcome the limits of traditional therapy and achieve higher cancer therapeutic efficacy that is successful in treating cervical cancer. Additionally, these therapies are safer than traditional therapy. Although many nanocarriers have been created, only a few numbers have received clinical approval to deliver anticancer medications to the targeted areas where their predicted activity is to be seen. Along with the patents released, various research reports illustrating the value of nanocarriers are addressed in this review. Some recent publications, clinical evidence, and patent records on nanocarrier architectures have been given, strengthening the understanding of tumor management.
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来源期刊
Current Nanoscience
Current Nanoscience 工程技术-材料科学:综合
CiteScore
3.50
自引率
6.70%
发文量
83
审稿时长
4.4 months
期刊介绍: Current Nanoscience publishes (a) Authoritative/Mini Reviews, and (b) Original Research and Highlights written by experts covering the most recent advances in nanoscience and nanotechnology. All aspects of the field are represented including nano-structures, nano-bubbles, nano-droplets and nanofluids. Applications of nanoscience in physics, material science, chemistry, synthesis, environmental science, electronics, biomedical nanotechnology, biomedical engineering, biotechnology, medicine and pharmaceuticals are also covered. The journal is essential to all researches involved in nanoscience and its applied and fundamental areas of science, chemistry, physics, material science, engineering and medicine. Current Nanoscience also welcomes submissions on the following topics of Nanoscience and Nanotechnology: Nanoelectronics and photonics Advanced Nanomaterials Nanofabrication and measurement Nanobiotechnology and nanomedicine Nanotechnology for energy Sensors and actuator Computational nanoscience and technology.
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