【以局部鼻糜烂为首发临床表现的寻常型天疱疮1例】

Q3 Medicine
Ayaka Kaneoka, Y. Sawada
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引用次数: 2

摘要

一位73岁的男性发现了局部的鼻子腐蚀,我们认为这可能是由于戴口罩摩擦的直接影响而加剧的皮肤腐蚀。血液检查显示血清抗粘连蛋白1和抗粘连蛋白3抗体明显升高。皮肤活检显示表皮颗粒层棘层溶解。根据临床表现和实验室检查,我们诊断为抗粘连蛋白1和抗粘连蛋白3抗体阳性的寻常型天疱疮。口服强的松龙和硫唑嘌呤对皮肤疹反应良好,并逐渐改善。在这种情况下,天疱疮被认为是鉴别诊断的候选人,其中戴口罩的直接机械摩擦被认为是皮肤爆发的加剧因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[A Case of Pemphigus Vulgaris Showing a Local Nose Erosion as the First Clinical Manifestation].
A 73-year-old male noticed a localized nose erosion that we thought was possibly an exacerbation of skin erosion due to the direct influence of friction from wearing a mask. Blood examination revealed a remarkable increase in serum anti-desmoglein-1 and anti-desmoglein-3 antibodies. A skin biopsy showed acantholysis in the epidermal granular layer. Based on the clinical manifestation and laboratory examination, we diagnosed his eruption as anti-desmoglein-1 and anti-desmoglein-3 antibody - positive pemphigus vulgaris. His skin eruption responded well to oral prednisolone and azathioprine and gradually improved. Pemphigus was a candidate as a differential diagnosis in this case, in which the direct mechanical friction from wearing a mask was thought to be an exacerbating factor of skin eruption.
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来源期刊
Journal of UOEH
Journal of UOEH Medicine-Medicine (all)
CiteScore
1.30
自引率
0.00%
发文量
35
期刊介绍: Published quarterly: 1 annual volume consisted of 4 numbers. Issued on the 1st of March, June, September and December, respectively.
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