鸡冠提取物治疗手掌砷性角化病的疗效观察

IF 0.9 4区医学 Q4 PHARMACOLOGY & PHARMACY

Bangladesh Journal of Pharmacology Pub Date : 2019-05-07 DOI:10.3329/BJP.V14I2.38421

Fatema Chowdhury Anny, M. Misbahuddin

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引用次数: 2

摘要

本研究的目的是检验鸡毛提取物治疗中度手掌砷性角化病（n=35）的效果。所有患者均使用鸡冠提取物软膏，每天局部涂抹两次，持续12周。通过电话和每位患者就诊期间定期监测药膏的依从性和不良反应。在治疗前后采集两个手掌的照片。在治疗开始前和治疗结束后，通过测量双手手掌的砷性角化结节大小来评估临床改善。研究前结节的平均（±SD）大小为33.6±16.8，研究完成后降至5.4±5.2。这一变化（减少84%）具有统计学意义。在本研究期间，没有任何患者报告有任何不良反应。总之，鸡冠提取物可以有效地用于手掌砷性角化症的局部治疗。

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Effect of cock’s comb extract in the treatment of palmar arsenical keratosis

The aim of this study was to examine the effect of cock’s comb extract in the treatment of moderate palmar arsenical keratosis (n = 35). All the patients were provided cock’s comb extract ointment to apply topically twice daily for 12 weeks. Adherence to the ointment and adverse effects were monitored regularly through the phone call and during the visit of each patient. Photographs of both palms were collected before and after treatment. Clinical improvement was assessed by measuring the arsenical keratotic nodular size of the both palms before starting the treatment and after completion of the treatment. The mean (± SD) sizes of the nodules before the study was 33.6 ± 16.8, which reduced to 5.4 ± 5.2 after completion of the study. This change (84% reduction) was statistically significant. None of the patients reported to any adverse effect during this study period. In conclusion, cock’s comb extract can be used effectively as a topical treatment of the palmar arsenical keratosis.

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来源期刊

Bangladesh Journal of Pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

1.50

自引率

18.80%

发文量

审稿时长

>12 weeks

期刊介绍： Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, peer-reviewed journal of the Bangladesh Pharmacological Society (BDPS). A scholarly publication is defined ''open access'' when there are no financial, legal or technical barriers to accessing it. Anyone can read, download, copy, distribute, print or use it in educational purpose within the legal agreements. Peer review of a manuscript means the evaluation of research work by one or more people with similar competences. It can be open or blind. We do the single-blind peer review. Our readers want to know the methodology used by the researchers which is very important to get the results. The video clip of one of the methodologies is prepared by the authors and submit it to publish.