{"title":"新合成的糠醛衍生物对细菌和白腐真菌的抑制作用","authors":"Jianlong Wang, W. Gu, Shi-fa Wang","doi":"10.26789/AEB.2019.01.002","DOIUrl":null,"url":null,"abstract":"New N-alkylfurfurylacetamides were synthesized and characterized from abundant biomass derived furfural by a simple and straightforward procedure with overall yields of 51 to 92%. The antimicrobial activity of the synthesized compounds were then investigated and it was found that N-benzyl-N-furfurylacetamide and N-cyclohexyl-N-furfurylacetamide showed promising activity against bacteria, particularly white-rot-fungi, suggesting a feasible new type of anti-fungal agent in applications to protection and conservation of cultural heritage.","PeriodicalId":36987,"journal":{"name":"Applied Environmental Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Inhibition of bacteria and white-rot-fungi by newly synthesized furfural derivatives\",\"authors\":\"Jianlong Wang, W. Gu, Shi-fa Wang\",\"doi\":\"10.26789/AEB.2019.01.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"New N-alkylfurfurylacetamides were synthesized and characterized from abundant biomass derived furfural by a simple and straightforward procedure with overall yields of 51 to 92%. The antimicrobial activity of the synthesized compounds were then investigated and it was found that N-benzyl-N-furfurylacetamide and N-cyclohexyl-N-furfurylacetamide showed promising activity against bacteria, particularly white-rot-fungi, suggesting a feasible new type of anti-fungal agent in applications to protection and conservation of cultural heritage.\",\"PeriodicalId\":36987,\"journal\":{\"name\":\"Applied Environmental Biotechnology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-02-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Environmental Biotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26789/AEB.2019.01.002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Agricultural and Biological Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Environmental Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26789/AEB.2019.01.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
引用次数: 2
摘要
以丰富的生物质糠醛为原料,用简单、直接的方法合成了n -烷基糠酰乙酰胺,总收率为51 ~ 92%。对合成的化合物进行抑菌活性研究,发现n -苄基- n -糠酰乙酰胺和n -环己基- n -糠酰乙酰胺对细菌特别是白腐菌具有良好的抑菌活性,为文物保护提供了一种可行的新型抑菌剂。
Inhibition of bacteria and white-rot-fungi by newly synthesized furfural derivatives
New N-alkylfurfurylacetamides were synthesized and characterized from abundant biomass derived furfural by a simple and straightforward procedure with overall yields of 51 to 92%. The antimicrobial activity of the synthesized compounds were then investigated and it was found that N-benzyl-N-furfurylacetamide and N-cyclohexyl-N-furfurylacetamide showed promising activity against bacteria, particularly white-rot-fungi, suggesting a feasible new type of anti-fungal agent in applications to protection and conservation of cultural heritage.