{"title":"简要概述了创新的透皮给药方法的渗透促进剂","authors":"Parmita Phaugat, Manish Dhall, Suchitra Nishal","doi":"10.53879/id.60.08.12392","DOIUrl":null,"url":null,"abstract":"The transdermal drug administration system represents a potent substitute for administering medications orally and is also designed to offer a substitute for hypodermic injections. Presently, three generations of penetration enhancer to permeate through skin are available 1st Generation embraces chemical approaches and pertain to augment the efficacy of the drug transferred across the integral skin, 2nd generation encompasses physical permeation technologies and 3rd generation consists of microneedle and needleless penetration enhancers. There is renewed interest in transdermal drug delivery. This review focuses on some existing novel approaches and the additive upshot of techniques for increasing the permeation of drugs via skin penetration. By using the right methods, drug carriers, or certain chemical agents, it is important to cause the stratum corneum to change physically or biomolecularly.","PeriodicalId":13409,"journal":{"name":"INDIAN DRUGS","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A CONCISE OUTLINE ON INNOVATIVE PERMEATION ENHANCERS IN TRANSDERMAL DRUG DELIVERY APPROACH\",\"authors\":\"Parmita Phaugat, Manish Dhall, Suchitra Nishal\",\"doi\":\"10.53879/id.60.08.12392\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The transdermal drug administration system represents a potent substitute for administering medications orally and is also designed to offer a substitute for hypodermic injections. Presently, three generations of penetration enhancer to permeate through skin are available 1st Generation embraces chemical approaches and pertain to augment the efficacy of the drug transferred across the integral skin, 2nd generation encompasses physical permeation technologies and 3rd generation consists of microneedle and needleless penetration enhancers. There is renewed interest in transdermal drug delivery. This review focuses on some existing novel approaches and the additive upshot of techniques for increasing the permeation of drugs via skin penetration. By using the right methods, drug carriers, or certain chemical agents, it is important to cause the stratum corneum to change physically or biomolecularly.\",\"PeriodicalId\":13409,\"journal\":{\"name\":\"INDIAN DRUGS\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"INDIAN DRUGS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53879/id.60.08.12392\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"INDIAN DRUGS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53879/id.60.08.12392","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
A CONCISE OUTLINE ON INNOVATIVE PERMEATION ENHANCERS IN TRANSDERMAL DRUG DELIVERY APPROACH
The transdermal drug administration system represents a potent substitute for administering medications orally and is also designed to offer a substitute for hypodermic injections. Presently, three generations of penetration enhancer to permeate through skin are available 1st Generation embraces chemical approaches and pertain to augment the efficacy of the drug transferred across the integral skin, 2nd generation encompasses physical permeation technologies and 3rd generation consists of microneedle and needleless penetration enhancers. There is renewed interest in transdermal drug delivery. This review focuses on some existing novel approaches and the additive upshot of techniques for increasing the permeation of drugs via skin penetration. By using the right methods, drug carriers, or certain chemical agents, it is important to cause the stratum corneum to change physically or biomolecularly.