重症肌无力患者抗体滴度和临床病程的变化回顾性研究

IF 1.3 Q4 NEUROSCIENCES

Progress in Neurology and Psychiatry Pub Date : 2022-01-01 DOI:10.1002/pnp.738

B. Berger, Nils Schröter

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引用次数: 1

摘要

重症肌无力（MG）是一种罕见的长期自身免疫性疾病，可导致肌肉无力；这种情况通常分为缓解期和复发期。尽管MG患者对免疫抑制疗法的治疗反应通常通过临床评分来监测，但识别监测治疗反应的血清学生物标志物可能会有所帮助。在此，作者探讨了MG患者乙酰胆碱受体（AChR）抗体滴度与临床严重程度变化之间的相关性，并讨论了其对临床实践的意义。

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Changes in antibody titers and clinical course in myasthenia gravis retrospective study

Myasthenia gravis (MG) is a rare, long‐term autoimmune disorder that causes muscle weakness; the condition typically has phases when it remits and phases when it relapses. Even though treatment response with regards to immunosuppressive therapies in MG patients is classically monitored by clinical scores, identification of a serological biomarker that monitors treatment response could be helpful. Here, the authors explore the correlation between acetylcholine receptor (AChR) antibody titers with changes in clinical severity in patients with MG and discuss the implications for clinical practice.

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来源期刊

Progress in Neurology and Psychiatry NEUROSCIENCES-

CiteScore

1.70

自引率

8.30%

发文量

期刊介绍： Progress in Neurology and Psychiatry is published nine times a year, and is a journal for specialists in secondary care, GPs with an interest in neurology and psychiatry, community psychiatric nurses and other specialist healthcare professionals. Articles cover management, news updates and opinion in all areas of neurology and psychiatry.