model4you:一个个性化治疗效果评估的R包

Q1 Social Sciences
H. Seibold, A. Zeileis, T. Hothorn
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引用次数: 11

摘要

估计治疗效果的典型模型假设对所有个体的治疗效果是相同的。基于模型的递归划分允许放宽这一假设,并估计分层处理效果(基于模型的树)甚至个性化处理效果(基于模型的森林)。使用基于模型的树,可以计算不同层次个体的治疗效果。地层是以数据驱动的方式发现的,并取决于个体的特征。基于模型的随机森林允许个体之间根据模型参数(例如截距和处理效果)进行相似性估计。然后,相似性度量可以用来估计个性化模型。R包model4you在两种随机分配的治疗方法的设置中实现这些分层和个性化模型,重点是易用性和可解释性,以便临床医生和其他用户可以采用他们通常用于估计平均治疗效果的模型,并通过几行代码获得易于理解和解释的可视化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
model4you: An R Package for Personalised Treatment Effect Estimation
Typical models estimating treatment effects assume that the treatment effect is the same for all individuals. Model-based recursive partitioning allows to relax this assumption and to estimate stratified treatment effects (model-based trees) or even personalised treatment effects (model-based forests). With model-based trees one can compute treatment effects for different strata of individuals. The strata are found in a data-driven fashion and depend on characteristics of the individuals. Model-based random forests allow for a similarity estimation between individuals in terms of model parameters (e.g. intercept and treatment effect). The similarity measure can then be used to estimate personalised models. The R package model4you implements these stratified and personalised models in the setting with two randomly assigned treatments with a focus on ease of use and interpretability so that clinicians and other users can take the model they usually use for the estimation of the average treatment effect and with a few lines of code get a visualisation that is easy to understand and interpret.
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来源期刊
Journal of Open Research Software
Journal of Open Research Software Social Sciences-Library and Information Sciences
CiteScore
6.50
自引率
0.00%
发文量
7
审稿时长
21 weeks
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