Cierre de orejuela izquierda frente a ACOD en pacientes mayores: an�lisis con emparejamiento por puntuaci�n de propensi�n

Introduction and objectives: Information comparing left atrial appendage closure (LAAC) to direct oral anticoagulation (DOAC) therapy is scarce. Our aim is to compare the clinical outcomes between LAAC and DOACs on an elderly population (> 80 years of age). Methods: We retrospectively collected 1144 octogenarian patients with atrial fibrillation from 3 different tertiary hospitals. A total of 970 patients received DOACs and 174 patients were treated with LAAC. At baseline, both groups had similar cardiovascular risk factors. The LAAC group had more history of bleeding, anemia or previous cancer. We conducted a propensity score matching study and obtained 2 different paired groups of 58 patients with similar baseline risk factors, comorbidities, and risk scores who received DOACs or were treated with LAAC. The outcomes of the therapeutic strategy used (DOACs or LAAC) were assessed using the Cox regression analysis. ARTICLE IN PRESS Cómo citar este artículo: Caneiro-Queija B, et al. Cierre de orejuela izquierda frente a ACOD en pacientes mayores: análisis con emparejamiento por puntuación de propensión. REC Interv Cardiol. 2022. https://doi.org/10.24875/RECIC.M22000316 2 B. Caneiro-Queija et al. REC Interv Cardiol. 20XX;XX(X):XX-XX