脾脏测量与死因和脾脏重量估计:死后计算机断层扫描的研究

Vasiliki Chatzaraki , Janette Verster , Carlo Tappero , Michael J Thali , Wolf Schweitzer , Garyfalia Ampanozi
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引用次数: 3

摘要

目的脾脏是人体最大的淋巴器官。尸体解剖时,它的外观和重量可能与死因的确定有关。死后计算机断层扫描(PMCT)是传统尸检的补充。本研究的目的是探讨PMCT的脾脏放射密度与先前住院、脾脏宏观检查、死亡原因以及PMCT在估计脾脏重量(SW)方面的作用。方法回顾性分析1035具尸体的PMCT轴向图像,评价脾脏密度、宽度(W)、厚度(T)、最大轴向面(S)和造影剂残留(CM)的存在。我们回顾了相应的尸检报告,包括死因、先前住院的证据、尸检时的SW和脾脏的宏观特征,如充血、苍白或收缩。结果CM患者PMCT上脾脏密度明显增高,医院死亡患者PMCT上脾脏密度明显降低。以多器官衰竭为死因的脾脏密度明显低于致死性出血、中毒、窒息-勒死、体温过低和代谢紊乱。不同的脾脏宏观表现没有明显的密度差异。脾脏W、T和S与尸检时的SW密切相关,并基于线性回归模型推导出估算SW的公式。结论CM、既往住院及脏器功能衰竭、致死性大出血、中毒、窒息-勒死、体温过低、代谢紊乱等死因对PMCT患者脾放射密度有影响。常规PMCT脾脏测量可用于在尸检前预测SW,或在未进行完整法医尸检时估计SW。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spleen measurements with reference to cause of death and spleen weight estimation: A study on postmortem computed tomography

Purpose The spleen is the largest lymphatic organ in the human body. Its appearance and weight during autopsy can be relevant for the determination of cause of death. Postmortem computed tomography (PMCT) supplements traditional autopsy. The aims of this study were to investigate spleen radiodensity on PMCT with regards to prior hospitalization, spleen macroscopy, cause of death, and the utility of PMCT for estimation of spleen weight (SW).

Methods Spleen density, width (W), thickness (T), greatest axial surface (S) and presence or absence of contrast medium (CM) residues were evaluated on PMCT axial images of 1035 cadavers retrospectively. Corresponding autopsy reports were reviewed for cause of death, evidence of prior hospitalization, SW at autopsy and macroscopic features of the spleen, like congestion, pallor or contraction.

Results Spleen density on PMCT was significantly higher for cases with CM and lower for hospital deaths. Multiple organ failure as cause of death showed significantly lower spleen density than fatal hemorrhage, intoxication, asphyxia-strangulation, hypothermia and metabolic disorders. No significant density differences were noted for different macroscopic spleen findings. Spleen W, T and S strongly correlate with SW at autopsy and formulas for estimating SW were derived based on linear regression models.

Conclusions Presence of CM, prior hospitalization and organ failure, fatal hemorrhage, intoxication, asphyxia-strangulation, hypothermia and metabolic disorders as causes of death have an influence on spleen's radiodensity on PMCT. Routine spleen measurements on PMCT can be used to predict SW prior to autopsy or estimate SW when complete forensic autopsy is not conducted.

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来源期刊
Journal of Forensic Radiology and Imaging
Journal of Forensic Radiology and Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
1.70
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