{"title":"益生菌混合物抑制碳水化合物消化的体外安全性和有效性","authors":"Eunsol Seo, Jang-Bin Woo, M. Seo, Jeongmin Woo","doi":"10.11002/kjfp.2023.30.3.538","DOIUrl":null,"url":null,"abstract":"\n \n This study aimed to assess the in vitro safety of a probiotics\n mixture (Lactobacillus acidophilus PBS066,\n Lactiplantibacillus plantarum PBS067, and\n Limosilactobacillus reuteri PBS072), along with its\n inhibitory effect on carbohydrate digestion. All three strains met the\n antibiotic resistance profile of the European Food Safety Authority (EFSA)\n guidelines. None of the strains exhibited hemolytic activity or cytotoxicity\n against Caco-2 cells. Strains PBS067 and PBS072 inhibited\n α-amylase activity, whereas all three strains\n suppressed α-glucosidase activity, indicating that the\n mixture might limit carbohydrate digestion in the gastrointestinal tract. These\n findings support the safety of this probiotics mixture and its potential to\n modulate carbohydrate metabolism in the gut.\n","PeriodicalId":17875,"journal":{"name":"Korean Journal of Food Preservation","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"In vitro safety and efficacy of probiotics mixture\\n on carbohydrate digestion inhibition\",\"authors\":\"Eunsol Seo, Jang-Bin Woo, M. Seo, Jeongmin Woo\",\"doi\":\"10.11002/kjfp.2023.30.3.538\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n \\n This study aimed to assess the in vitro safety of a probiotics\\n mixture (Lactobacillus acidophilus PBS066,\\n Lactiplantibacillus plantarum PBS067, and\\n Limosilactobacillus reuteri PBS072), along with its\\n inhibitory effect on carbohydrate digestion. All three strains met the\\n antibiotic resistance profile of the European Food Safety Authority (EFSA)\\n guidelines. None of the strains exhibited hemolytic activity or cytotoxicity\\n against Caco-2 cells. Strains PBS067 and PBS072 inhibited\\n α-amylase activity, whereas all three strains\\n suppressed α-glucosidase activity, indicating that the\\n mixture might limit carbohydrate digestion in the gastrointestinal tract. These\\n findings support the safety of this probiotics mixture and its potential to\\n modulate carbohydrate metabolism in the gut.\\n\",\"PeriodicalId\":17875,\"journal\":{\"name\":\"Korean Journal of Food Preservation\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Korean Journal of Food Preservation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11002/kjfp.2023.30.3.538\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Agricultural and Biological Sciences\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Korean Journal of Food Preservation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11002/kjfp.2023.30.3.538","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Agricultural and Biological Sciences","Score":null,"Total":0}
In vitro safety and efficacy of probiotics mixture
on carbohydrate digestion inhibition
This study aimed to assess the in vitro safety of a probiotics
mixture (Lactobacillus acidophilus PBS066,
Lactiplantibacillus plantarum PBS067, and
Limosilactobacillus reuteri PBS072), along with its
inhibitory effect on carbohydrate digestion. All three strains met the
antibiotic resistance profile of the European Food Safety Authority (EFSA)
guidelines. None of the strains exhibited hemolytic activity or cytotoxicity
against Caco-2 cells. Strains PBS067 and PBS072 inhibited
α-amylase activity, whereas all three strains
suppressed α-glucosidase activity, indicating that the
mixture might limit carbohydrate digestion in the gastrointestinal tract. These
findings support the safety of this probiotics mixture and its potential to
modulate carbohydrate metabolism in the gut.
期刊介绍:
This journal aims to promote and encourage the advancement of quantitative improvement for the storage, processing and distribution of food and its related disciplines, theory and research on its application. Topics covered include: Food Preservation and Packaging Food and Food Material distribution Fresh-cut Food Manufacturing Food processing Technology Food Functional Properties Food Quality / Safety.