基于正念的药物滥用治疗(MBSAT)改善青少年药物使用障碍的执行功能

Q3 Medicine
Jaber Alizadehgoradel , Saeed Imani , Vahid Nejati , Jalil Fathabadi
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引用次数: 8

摘要

研究表明,通过正念练习治疗药物滥用是有希望的。然而,正念练习治疗物质使用障碍的神经机制尚不清楚。有证据表明,执行功能的重大缺陷,如抑制控制、冒险行为和决策、心理灵活性和工作记忆,都与吸毒的渴望有关。目前的研究旨在调查正念练习对改善执行功能的功效,通过神经科学工具进行评估,研究对象是一组有甲基苯丙胺使用障碍的青少年。方法选择18 ~ 21岁甲基苯丙胺使用障碍青少年40例,随机分为实验组(n = 20)和对照组(n = 20)。受试者接受三次评估:干预前、治疗后和治疗后一个月。基于正念的药物滥用治疗(MBSAT)进行了12次治疗,每周两次50-60 分钟的治疗。结果混合模型方差分析显示,与对照组相比,正念干预改善了实验组的执行功能。结论:本研究首次支持正念练习在改善甲基苯丙胺使用障碍青少年执行功能方面的益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mindfulness-based substance abuse treatment (MBSAT) improves executive functions in adolescents with substance use disorders

Objective

Studies show promise for the treatment of substance abuse through mindfulness practice. However, the neural mechanisms of mindfulness practice for treating substance use disorders are still unclear. Evidence suggests that major deficits in executive functions such as inhibitory control, risky behavior and decision-making, psychological flexibility, and working memory are associated with a craving to use. The current study aims to investigate the efficacy of mindfulness practice on improving executive functions, assessed by neuroscientific tools, in a group of adolescents with methamphetamine use disorders.

Method

Forty adolescents (18–21 years old) with methamphetamine use disorders were selected and randomly assigned to experimental (n = 20) and control groups (n = 20). Subjects were assessed three times: before the intervention, immediately after and one month after treatment. Mindfulness-based substance abuse treatment (MBSAT) was administered for 12 sessions, two 50–60 minutes sessions per week.

Results

Results Mixed model ANOVAs analysis showed that mindfulness-based intervention improved executive functions in the experimental group compared to controls.

Conclusions

This study is the first to support the benefits of mindfulness-based practice in improving executive functions of adolescents with methamphetamine use disorders.

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期刊介绍: Neurology, Psychiatry & Brain Research publishes original papers and reviews in biological psychiatry, brain research, neurology, neuropsychiatry, neuropsychoimmunology, psychopathology, psychotherapy. The journal has a focus on international and interdisciplinary basic research with clinical relevance. Translational research is particularly appreciated. Authors are allowed to submit their manuscript in their native language as supplemental data to the English version. Neurology, Psychiatry & Brain Research is related to the oldest German speaking journal in this field, the Centralblatt fur Nervenheilkunde, Psychiatrie und gerichtliche Psychopathologie, founded in 1878. The tradition and idea of previous famous editors (Alois Alzheimer and Kurt Schneider among others) was continued in modernized form with Neurology, Psychiatry & Brain Research. Centralblatt was a journal of broad scope and relevance, now Neurology, Psychiatry & Brain Research represents a journal with translational and interdisciplinary perspective, focusing on clinically oriented research in psychiatry, neurology and neighboring fields of neurosciences and psychology/psychotherapy with a preference for biologically oriented research including basic research. Preference is given for papers from newly emerging fields, like clinical psychoimmunology/neuroimmunology, and ideas.
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