Jaber Alizadehgoradel , Saeed Imani , Vahid Nejati , Jalil Fathabadi
{"title":"基于正念的药物滥用治疗(MBSAT)改善青少年药物使用障碍的执行功能","authors":"Jaber Alizadehgoradel , Saeed Imani , Vahid Nejati , Jalil Fathabadi","doi":"10.1016/j.npbr.2019.08.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Studies show promise for the treatment of substance abuse through mindfulness practice. However, the neural mechanisms of mindfulness practice for treating substance use disorders are still unclear. Evidence suggests that major deficits in executive functions such as inhibitory control, risky behavior and decision-making, psychological flexibility, and working memory are associated with a craving to use. The current study aims to investigate the efficacy of mindfulness practice on improving executive functions, assessed by neuroscientific tools, in a group of adolescents with methamphetamine use disorders.</p></div><div><h3>Method</h3><p>Forty adolescents (18–21 years old) with methamphetamine use disorders were selected and randomly assigned to experimental (n = 20) and control groups (n = 20). Subjects were assessed three times: before the intervention, immediately after and one month after treatment. Mindfulness-based substance abuse treatment (MBSAT) was administered for 12 sessions, two 50–60 minutes sessions per week.</p></div><div><h3>Results</h3><p>Results Mixed model ANOVAs analysis showed that mindfulness-based intervention improved executive functions in the experimental group compared to controls.</p></div><div><h3>Conclusions</h3><p>This study is the first to support the benefits of mindfulness-based practice in improving executive functions of adolescents with methamphetamine use disorders.</p></div>","PeriodicalId":49756,"journal":{"name":"Neurology Psychiatry and Brain Research","volume":"34 ","pages":"Pages 13-21"},"PeriodicalIF":0.0000,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.npbr.2019.08.002","citationCount":"8","resultStr":"{\"title\":\"Mindfulness-based substance abuse treatment (MBSAT) improves executive functions in adolescents with substance use disorders\",\"authors\":\"Jaber Alizadehgoradel , Saeed Imani , Vahid Nejati , Jalil Fathabadi\",\"doi\":\"10.1016/j.npbr.2019.08.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Studies show promise for the treatment of substance abuse through mindfulness practice. However, the neural mechanisms of mindfulness practice for treating substance use disorders are still unclear. Evidence suggests that major deficits in executive functions such as inhibitory control, risky behavior and decision-making, psychological flexibility, and working memory are associated with a craving to use. The current study aims to investigate the efficacy of mindfulness practice on improving executive functions, assessed by neuroscientific tools, in a group of adolescents with methamphetamine use disorders.</p></div><div><h3>Method</h3><p>Forty adolescents (18–21 years old) with methamphetamine use disorders were selected and randomly assigned to experimental (n = 20) and control groups (n = 20). Subjects were assessed three times: before the intervention, immediately after and one month after treatment. Mindfulness-based substance abuse treatment (MBSAT) was administered for 12 sessions, two 50–60 minutes sessions per week.</p></div><div><h3>Results</h3><p>Results Mixed model ANOVAs analysis showed that mindfulness-based intervention improved executive functions in the experimental group compared to controls.</p></div><div><h3>Conclusions</h3><p>This study is the first to support the benefits of mindfulness-based practice in improving executive functions of adolescents with methamphetamine use disorders.</p></div>\",\"PeriodicalId\":49756,\"journal\":{\"name\":\"Neurology Psychiatry and Brain Research\",\"volume\":\"34 \",\"pages\":\"Pages 13-21\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.npbr.2019.08.002\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neurology Psychiatry and Brain Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0941950019300958\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neurology Psychiatry and Brain Research","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0941950019300958","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Mindfulness-based substance abuse treatment (MBSAT) improves executive functions in adolescents with substance use disorders
Objective
Studies show promise for the treatment of substance abuse through mindfulness practice. However, the neural mechanisms of mindfulness practice for treating substance use disorders are still unclear. Evidence suggests that major deficits in executive functions such as inhibitory control, risky behavior and decision-making, psychological flexibility, and working memory are associated with a craving to use. The current study aims to investigate the efficacy of mindfulness practice on improving executive functions, assessed by neuroscientific tools, in a group of adolescents with methamphetamine use disorders.
Method
Forty adolescents (18–21 years old) with methamphetamine use disorders were selected and randomly assigned to experimental (n = 20) and control groups (n = 20). Subjects were assessed three times: before the intervention, immediately after and one month after treatment. Mindfulness-based substance abuse treatment (MBSAT) was administered for 12 sessions, two 50–60 minutes sessions per week.
Results
Results Mixed model ANOVAs analysis showed that mindfulness-based intervention improved executive functions in the experimental group compared to controls.
Conclusions
This study is the first to support the benefits of mindfulness-based practice in improving executive functions of adolescents with methamphetamine use disorders.
期刊介绍:
Neurology, Psychiatry & Brain Research publishes original papers and reviews in
biological psychiatry,
brain research,
neurology,
neuropsychiatry,
neuropsychoimmunology,
psychopathology,
psychotherapy.
The journal has a focus on international and interdisciplinary basic research with clinical relevance. Translational research is particularly appreciated. Authors are allowed to submit their manuscript in their native language as supplemental data to the English version.
Neurology, Psychiatry & Brain Research is related to the oldest German speaking journal in this field, the Centralblatt fur Nervenheilkunde, Psychiatrie und gerichtliche Psychopathologie, founded in 1878. The tradition and idea of previous famous editors (Alois Alzheimer and Kurt Schneider among others) was continued in modernized form with Neurology, Psychiatry & Brain Research. Centralblatt was a journal of broad scope and relevance, now Neurology, Psychiatry & Brain Research represents a journal with translational and interdisciplinary perspective, focusing on clinically oriented research in psychiatry, neurology and neighboring fields of neurosciences and psychology/psychotherapy with a preference for biologically oriented research including basic research. Preference is given for papers from newly emerging fields, like clinical psychoimmunology/neuroimmunology, and ideas.