{"title":"干细胞在治疗新冠肺炎相关器官损伤中的作用评估","authors":"E. Bryant, V. Gallicchio","doi":"10.52793/jscr.2021.2(2)-22","DOIUrl":null,"url":null,"abstract":"COVID-19 is an illness that can produce life-threatening complications in hosts. It is caused by the SARS-CoV-2 coronavirus. This work examines and compares existing publications covering the usage of stem cells in the research and treatment of COVID-19 symptoms. Specifically, hPSCs serve a purpose centered on research as they are incorporated into determining pathophysiology of COVID-19; whereas MSC injections are being developed as medical treatments. hPSCs have been utilized to form artificial organoids crucial to the study of COVID-19 effects on the cardiovascular, pulmonary, renal, gastrointestinal, and neural systems. The ability of MSCs to regenerate tissue and communicate with the host immune system to induce anti-inflammatory effects makes them key in medical studies during which MSC solutions are injected into COVID-19-infected patients. The results of these studies, though incomplete, show that MSCs are capable of alleviating COVID-19 symptoms. Both hPSCs and MSCs are therefore","PeriodicalId":92258,"journal":{"name":"Journal of stem cell research","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation Of The Role Of Stem Cells In Treatments For Organ Damage Related To COVID-19\",\"authors\":\"E. Bryant, V. Gallicchio\",\"doi\":\"10.52793/jscr.2021.2(2)-22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"COVID-19 is an illness that can produce life-threatening complications in hosts. It is caused by the SARS-CoV-2 coronavirus. This work examines and compares existing publications covering the usage of stem cells in the research and treatment of COVID-19 symptoms. Specifically, hPSCs serve a purpose centered on research as they are incorporated into determining pathophysiology of COVID-19; whereas MSC injections are being developed as medical treatments. hPSCs have been utilized to form artificial organoids crucial to the study of COVID-19 effects on the cardiovascular, pulmonary, renal, gastrointestinal, and neural systems. The ability of MSCs to regenerate tissue and communicate with the host immune system to induce anti-inflammatory effects makes them key in medical studies during which MSC solutions are injected into COVID-19-infected patients. The results of these studies, though incomplete, show that MSCs are capable of alleviating COVID-19 symptoms. Both hPSCs and MSCs are therefore\",\"PeriodicalId\":92258,\"journal\":{\"name\":\"Journal of stem cell research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-07-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of stem cell research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52793/jscr.2021.2(2)-22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of stem cell research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52793/jscr.2021.2(2)-22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation Of The Role Of Stem Cells In Treatments For Organ Damage Related To COVID-19
COVID-19 is an illness that can produce life-threatening complications in hosts. It is caused by the SARS-CoV-2 coronavirus. This work examines and compares existing publications covering the usage of stem cells in the research and treatment of COVID-19 symptoms. Specifically, hPSCs serve a purpose centered on research as they are incorporated into determining pathophysiology of COVID-19; whereas MSC injections are being developed as medical treatments. hPSCs have been utilized to form artificial organoids crucial to the study of COVID-19 effects on the cardiovascular, pulmonary, renal, gastrointestinal, and neural systems. The ability of MSCs to regenerate tissue and communicate with the host immune system to induce anti-inflammatory effects makes them key in medical studies during which MSC solutions are injected into COVID-19-infected patients. The results of these studies, though incomplete, show that MSCs are capable of alleviating COVID-19 symptoms. Both hPSCs and MSCs are therefore