对伴随症状性冠状动脉疾病和颈动脉狭窄的评论-塔夫茨医疗中心的经验

Y. Ikeno, K. Charlton-Ouw, M. Iafrati, Anand Y. Shah
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摘要

尽管手术结果有所改善,急性卒中仍然是冠状动脉旁路移植术(CABG)后的严重并发症。由于冠心病和颈动脉狭窄的共同背景是全身性动脉粥样硬化(20%),因此两者并存的情况很普遍。Naylor等[3,4]研究表明,无症状的单侧颈动脉严重狭窄患者CABG相关卒中的风险为3.2%,而双侧颈动脉狭窄患者的这一数字增加到5.2%,颈动脉闭塞患者的这一数字增加到7%至11.6%。随着时间的推移,冠心病和颈动脉疾病的治疗已经得到了阐明。颈动脉内膜切除术(CEA)和CABG在同一手术环境下的联合应用于20世纪80年代[5]。尽管如此,手术治疗,特别是手术的时间和顺序,在北美各地仍然各不相同。这篇评论反映了Tufts医学中心目前对并发CAD和颈动脉疾病患者围手术期卒中预防知识的经验,重点是同时进行CEA/CABG。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Commentary on Concomitant Symptomatic Coronary Disease and Carotid Artery Stenosis -The Tufts Medical Center Experience
135 Despite the development of surgical outcomes, acute stroke remain a devastating complication following coronary artery bypass grafting (CABG) [1]. Coexistent CAD and carotid artery stenosis are prevalent due to their common background of systemic atherosclerosis (20%) [2]. Naylor, et al. [3,4] demonstrated that the risk of stroke associated with CABG is 3.2% in patients with asymptomatic, unilateral severe carotid stenosis, whereas these figures increase to 5.2% in those with bilateral carotid stenosis and 7% to 11.6% in those with carotid occlusion. The management of concomitant CAD and carotid artery disease has been elucidated over time. The combination of carotid endarterectomy (CEA) and CABG in the same surgical setting was introduced in the 1980s [5]. Nonetheless, the surgical management, particularly the timing and order of surgical procedures, remains varied across North America. This commentary reflects upon the Tufts Medical Center experience on the current knowledge of the prevention of perioperative stroke in patients with concurrent CAD and carotid artery disease, focusing on simultaneous CEA/CABG.
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