具有协同抗菌性能的ZnO/Ag纳米粒子负载聚多巴胺改性蒙脱土纳米复合材料的研制

IF 5.3 2区 地球科学 Q2 CHEMISTRY, PHYSICAL
Han Liang , Huiyan Wang , Xuemei Sun , Wang Xu , Na Meng , Ninglin Zhou
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引用次数: 0

摘要

纳米复合材料是治疗微生物感染的有效方法。本文采用简单温和的方法合成了氧化锌纳米粒子和银纳米粒子,并成功地将其负载在聚多巴胺修饰的蒙脱土(PDAMt)上,制备了具有强抗菌能力的ZnO/Ag/PDA-Mt纳米复合材料。透射电镜(TEM)分析表明,ZnO/Ag/PDA-Mt纳米颗粒呈准球形,粒径在5 ~ 45 nm之间。能谱分析(EDS)证实合成的ZnO/Ag/PDA-Mt中存在Zn、Ag、O、Al、Si和C元素。此外,还测试了氧化锌/银/PDA-Mt对大肠杆菌(E. coli)和金黄色葡萄球菌(S. aureus)的抑菌活性。由于氧化锌纳米粒子和银纳米粒子之间的协同抗菌作用,ZnO/Ag/PDA-Mt比银纳米粒子负载的聚多巴胺修饰蒙脱土(Ag/PDA-Mt)和氧化锌纳米粒子负载的聚多巴胺修饰蒙脱土(ZnO/PDA-Mt)具有更高的抗菌活性。采用细胞毒性试验评价ZnO/Ag/PDA-Mt的生物相容性。结果表明,ZnO/Ag/PDA-Mt纳米复合材料具有潜在的抗菌应用前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Development of ZnO/Ag nanoparticles supported polydopamine-modified montmorillonite nanocomposites with synergistic antibacterial performance

Development of ZnO/Ag nanoparticles supported polydopamine-modified montmorillonite nanocomposites with synergistic antibacterial performance

Nanocomposites are effective methods for the treatment of microbial infections. In this work, zinc oxide nanoparticles and silver nanoparticles were synthesized by a simple and mild method, and successfully loaded on polydopamine-modified montmorillonite (PDAMt) to prepare nanocomposites (ZnO/Ag/PDA-Mt) with potent antibacterial ability. The transmission electron microscope (TEM) showed that the nanoparticles in ZnO/Ag/PDA-Mt were quasi-spherical, and the particle size ranged from 5 nm to 45 nm. The energy dispersive spectroscopy (EDS)-mapping verified the presence of Zn, Ag, O, Al, Si and C elements in the synthesized ZnO/Ag/PDA-Mt. In addition, the antimicrobial activity of ZnO/Ag/PDA-Mt was also tested against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). Due to the synergistic antibacterial effect between zinc oxide nanoparticles and silver nanoparticles, ZnO/Ag/PDA-Mt exhibited higher antiseptic activity than silver nanoparticles supported polydopamine-modified montmorillonite (Ag/PDA-Mt) and zinc oxide nanoparticles supported polydopamine-modified montmorillonite (ZnO/PDA-Mt). The biocompatibility of ZnO/Ag/PDA-Mt was evaluated by cytotoxicity assay. The results demonstrated that the ZnO/Ag/PDA-Mt nanocomposites have potential for antibacterial applications.

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来源期刊
Applied Clay Science
Applied Clay Science 地学-矿物学
CiteScore
10.30
自引率
10.70%
发文量
289
审稿时长
39 days
期刊介绍: Applied Clay Science aims to be an international journal attracting high quality scientific papers on clays and clay minerals, including research papers, reviews, and technical notes. The journal covers typical subjects of Fundamental and Applied Clay Science such as: • Synthesis and purification • Structural, crystallographic and mineralogical properties of clays and clay minerals • Thermal properties of clays and clay minerals • Physico-chemical properties including i) surface and interface properties; ii) thermodynamic properties; iii) mechanical properties • Interaction with water, with polar and apolar molecules • Colloidal properties and rheology • Adsorption, Intercalation, Ionic exchange • Genesis and deposits of clay minerals • Geology and geochemistry of clays • Modification of clays and clay minerals properties by thermal and physical treatments • Modification by chemical treatments with organic and inorganic molecules(organoclays, pillared clays) • Modification by biological microorganisms. etc...
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