影响无综合征性口面裂胎儿父母妊娠决策的因素:对中国夫妇的研究

IF 0.4 4区 医学 Q4 OBSTETRICS & GYNECOLOGY
Huanhuan Ding, Weizeng Zheng, Xinfen Xu, Baohua Li
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引用次数: 0

摘要

背景:当胎儿被诊断为面部畸形时,大多数中国夫妇会选择终止妊娠。然而,这些夫妇通常会在终止妊娠后后悔自己的决定,表现出更严重的悲伤,并且这种感觉会持续很长时间。本研究的目的是调查影响父母对诊断为非综合征性口唇腭裂(NSOFC)胎儿的妊娠决定的因素,并为制定有助于该领域进一步定性研究的访谈提纲提供初步基础。方法:我们收集了2013年1月至2019年7月来自中国一家妇女医院产科的400对夫妇的医疗记录,这些夫妇的胎儿被诊断为奥面裂。在排除那些报告染色体或其他异常的记录后,311例病例被纳入本研究。在单因素分析后,使用二元分类回归分析对可能影响父母怀孕决定的因素进行了分析。结果:311对夫妇中,71.7%(223/311)决定终止妊娠,28.3%(88/311)选择继续妊娠。户籍、NSOFC家族史、可能导致胎儿患NSOFC的母亲高危因素、母亲年龄、父亲年龄、医生建议、产前诊断和首次诊断的孕周均影响妊娠决策(p<0.05),产前诊断和首次诊断的孕周对父母的妊娠决定有很大影响。讨论:农村户籍、无NSOFC家族史、无孕产妇高危因素、产妇年龄较小、初诊胎龄较小的夫妇终止妊娠的相对风险较大。产前诊断是一个保护因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors influencing parental pregnancy decision-making due to fetuses with non-syndromic orofacial clefts: a study of Chinese couples
Background: When a fetus is diagnosed with facial deformities, most Chinese couples choose to terminate the pregnancy. However, these couples commonly regret their decision after the termination of the pregnancy, display a heavier degree of grief, and these feelings persist for a long time. The purpose of this study was to investigate factors that influence parental pregnancy decisions regarding fetuses diagnosed with a non-syndromic orofacial cleft (NSOFC), and to provide the preliminary basis for a formulation of interview outlines useful in further qualitative research in this area. Methods: We collected medical records of 400 couples from the obstetrical units of a women’s hospital in China whose fetuses were diagnosed with Orofacial clefts (OFCs) from January 2013 to July 2019. After excluding those records reporting chromosomal or other abnormalities, 311 cases were included in this study. After univariate analysis, factors that may have affected the parental pregnancy decision were analyzed using binary classification regression analysis. Results: Among the 311 couples, 71.7% (223/311) decided to terminate the pregnancy, whereas 28.3% (88/311) decided to continue. The registered residence, family history of NSOFC, maternal high-risk factors that may lead to the fetus suffering from NSOFC, maternal age, paternal age, doctor’s suggestion, prenatal diagnosis, and first diagnosed gestational week all influenced pregnancy decision makings (p< 0.05). Among these, the registered residence, family history of NSOFC, maternal high-risk factors, maternal age, prenatal diagnosis, and first diagnosed gestational week substantially affected the parental pregnancy decision. Discussion: The couples with registered residence in rural areas, no family history of NSOFC, no maternal high-risk factors, younger maternal age, younger gestational age at first diagnosis are at greater relative risk of pregnancy termination. Prenatal diagnosis is a protective factor.
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
241
审稿时长
1 months
期刊介绍: CEOG is an international, peer-reviewed, open access journal. CEOG covers all aspects of Obstetrics and Gynecology, including obstetrics, prenatal diagnosis, maternal-fetal medicine, perinatology, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine, infertility, reproductive endocrinology, sexual medicine. All submissions of cutting-edge advances of medical research in the area of women''s health worldwide are encouraged.
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