Potential Risk Factors of the Cognitive Dysfunction in Patients with Type 2 Diabetes Mellitus

Abstract It is known that the aged persons with type 2 diabetes mellitus present a high risk for developing neurocognitive disorders and in order to explain this phenomenon we have proposed some potential risk factors. They can be involved in the causality patterns or can act as useful markers of the cerebrovascular lesions (or both) and for which there are strong proofs, including the poor glycemic control, hypoglycemia, microvascular diseases, inflammation or depression. For the macrovascular affections, the association with the cognitive disorders seems to devolve on the examined vascular system. It is put into discussion that for the next researches it is important to analyze how exactly the interrelations between the risk factors can contribute to cognitive disorders.