使用正丁基-2-氰基丙烯酸酯在耶和华见证人病人的微血管减压。

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-12-01 Epub Date: 2022-04-09 DOI:10.1080/02688697.2022.2061913
Ryuzaburo Kanazawa, Takanori Uchida, Tetsuhiro Higashida, Saiko Watanabe, Yuichi Takahashi, Kei Yamazaki
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引用次数: 0

摘要

目的报告一名耶和华见证人患者在微血管减压手术中应用正丁基-2-氰基丙烯酸酯(n-BCA)。据我们所知,这是第一例使用n-BCA作为粘接剂粘附到病变动脉的病例。病例介绍:一名55岁的耶和华见证会女性患者患有严重的右半面肌痉挛。虽然需要进行MVD手术,但患者拒绝使用包括纤维蛋白胶在内的全血制品进行治疗。因此,我们提出了几种使用人工材料的选择,包括n-BCA作为粘合剂,并获得了患者的知情同意。结果对右椎动脉和右小脑后下动脉进行超声造影。手术过程中异常血管反应消失,相关血管的n-BCA转位成功。患者经历了良好的术后临床过程,并已摆脱痉挛一年。随访期间放射学检查未见异常。结论:尽管必须仔细随访,但n-BCA是MVD手术中可能的替代选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Use of n-butyl-2-cyanoacrylate for microvascular decompression in a Jehovah's witness patient.

Objective: We report the application of n-butyl-2-cyanoacrylate (n-BCA) in microvascular decompression (MVD) surgery for a Jehovah's Witness patient. To our best knowledge, this is the first case wherein n-BCA has been employed as an adhesive to the offending artery.

Case presentation: A 55-year-old female Jehovah's Witness patient was suffering from serious right hemifacial spasm. Although MVD surgery was needed, the patient resisted any curative medical treatment involving the application of whole blood products, including fibrin glue. Thus, we proposed several choices using artificial materials, including n-BCA as an adhesive, and received informed consent from the patient.

Result: MVD was performed on the dolichoectatic right vertebral artery and right posterior inferior cerebellar artery. The abnormal vessel response disappeared during the procedure and transposition using n-BCA of the concerned vessels was successful. The patient experienced a favorable postoperative clinical course and has been free from the spasm for a year. No abnormal findings were detected in the radiological examination during the follow-up period.

Conclusion: Although careful follow-up is mandatory, n-BCA is a possible alternative option in MVD surgery.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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