Potential of S-Allyl Cysteine, a Major Bioactive Component of Garlic, As Hypoglycemic and Hypolipidemic Agent

Diabetes Mellitus (DM) is a global health issue characterized by hyperglycemia, insulin resistance, absolute or relative impairment in insulin secretion, action or both. Diabetes and insulin resistance have a close association with body mass index, and the increasing occurrence of DM is linked to weight gain and body mass. Treatment options are very unsatisfactory having multiple adverse effects. S-Allyl cysteine (SAC) is an organic compound and a natural constituent of Allium sativum, commonly known as garlic, and is widely acknowledged to have a variety of biological activities with minimal side effects. The aim of this study was to review the hypoglycemic and hypolipidemic effects of SAC, a sulfurcontaining amino acid.