血友病合并抑制剂烧伤手术的管理策略:一例报告

Q3 Medicine
L. Kearney , M. Abrahams , N. O'Connell , O.P. Shelley
{"title":"血友病合并抑制剂烧伤手术的管理策略:一例报告","authors":"L. Kearney ,&nbsp;M. Abrahams ,&nbsp;N. O'Connell ,&nbsp;O.P. Shelley","doi":"10.1016/j.burnso.2023.08.003","DOIUrl":null,"url":null,"abstract":"<div><p>Few reports exist in the literature dealing with the management of acute burns in the hemophilic patient [1–4]. Burns treatment in this population group is an obvious challenge, due to the recognized major blood loss that can result from both the burns excision and harvesting split thickness skin grafts. Recent proposed strategies have suggested structured factor replacement during multiple radical short operations [3]. We describe a particularly challenging case, a person with mild Factor VIII deficiency (Hemophilia A) with a history of a high responding inhibitor and cross-reactivity with standard Factor VIII products. We propose a management strategy to optimise care and reduce bleeding related complications in these patients.</p></div>","PeriodicalId":72486,"journal":{"name":"Burns open : an international open access journal for burn injuries","volume":"7 4","pages":"Pages 114-116"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A management strategy for burns surgery in hemophilia complicated by inhibitors: A case report\",\"authors\":\"L. Kearney ,&nbsp;M. Abrahams ,&nbsp;N. O'Connell ,&nbsp;O.P. Shelley\",\"doi\":\"10.1016/j.burnso.2023.08.003\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Few reports exist in the literature dealing with the management of acute burns in the hemophilic patient [1–4]. Burns treatment in this population group is an obvious challenge, due to the recognized major blood loss that can result from both the burns excision and harvesting split thickness skin grafts. Recent proposed strategies have suggested structured factor replacement during multiple radical short operations [3]. We describe a particularly challenging case, a person with mild Factor VIII deficiency (Hemophilia A) with a history of a high responding inhibitor and cross-reactivity with standard Factor VIII products. We propose a management strategy to optimise care and reduce bleeding related complications in these patients.</p></div>\",\"PeriodicalId\":72486,\"journal\":{\"name\":\"Burns open : an international open access journal for burn injuries\",\"volume\":\"7 4\",\"pages\":\"Pages 114-116\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Burns open : an international open access journal for burn injuries\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2468912223000317\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Burns open : an international open access journal for burn injuries","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468912223000317","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

文献中很少有关于血友病患者急性烧伤处理的报道[1-4]。在这一人群中,烧伤治疗是一个明显的挑战,因为公认的主要失血可能是由于烧伤切除和收获分厚皮肤移植造成的。最近提出的策略建议在多次根治性短期手术中进行结构性因子置换[3]。我们描述了一个特别具有挑战性的案例,一个患有轻度因子VIII缺乏症(血友病a)的人,具有高反应抑制剂和标准因子VIII产品交叉反应的历史。我们提出一个管理策略,以优化护理和减少出血相关的并发症在这些患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A management strategy for burns surgery in hemophilia complicated by inhibitors: A case report

Few reports exist in the literature dealing with the management of acute burns in the hemophilic patient [1–4]. Burns treatment in this population group is an obvious challenge, due to the recognized major blood loss that can result from both the burns excision and harvesting split thickness skin grafts. Recent proposed strategies have suggested structured factor replacement during multiple radical short operations [3]. We describe a particularly challenging case, a person with mild Factor VIII deficiency (Hemophilia A) with a history of a high responding inhibitor and cross-reactivity with standard Factor VIII products. We propose a management strategy to optimise care and reduce bleeding related complications in these patients.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.20
自引率
0.00%
发文量
0
审稿时长
15 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信